HIF-2α is essential for carotid body development and function

HIF-2α is essential for carotid body development and function

Mammalian adaptation to oxygen flux occurs at many levels, from shifts in cellular metabolism to physiological adaptations facilitated by the sympathetic nervous system and carotid body (CB). Interactions between differing forms of adaptive response to hypoxia, including transcriptional responses or...

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Bibliographic Details
Main Authors: David Macias, Andrew S Cowburn, Hortensia Torres-Torrelo, Patricia Ortega-Sáenz, José López-Barneo, Randall S Johnson
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-04-01
Series:eLife
Subjects:
hypoxia
carotid body
sympathetic nerves
Online Access:https://elifesciences.org/articles/34681

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