Phaeohyphomycosis Caused by Phaeoacremoniumrubrigenum in an Immunosuppressive Patient: A Case Report and Review of the Literature

Phaeohyphomycosis (PHM) is a rare, deep fungal infection of the skin and subcutaneous tissues caused by dematiaceous fungi. In this report, we describe a case of PHM caused by Phaeoacremoniumrubrigenum, which is generally known to infect woody plants. We detected the gray-blackish villi by biopsy cu...

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Main Authors: Sadanori Furudate, Shu Sasai, Yukikazu Numata, Taku Fujimura, Setsuya Aiba
Format: Article
Language:English
Published: Karger Publishers 2012-06-01
Series:Case Reports in Dermatology
Subjects:
Online Access:http://www.karger.com/Article/FullText/339622
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author Sadanori Furudate
Shu Sasai
Yukikazu Numata
Taku Fujimura
Setsuya Aiba
author_facet Sadanori Furudate
Shu Sasai
Yukikazu Numata
Taku Fujimura
Setsuya Aiba
author_sort Sadanori Furudate
collection DOAJ
description Phaeohyphomycosis (PHM) is a rare, deep fungal infection of the skin and subcutaneous tissues caused by dematiaceous fungi. In this report, we describe a case of PHM caused by Phaeoacremoniumrubrigenum, which is generally known to infect woody plants. We detected the gray-blackish villi by biopsy culture material, and slide culture revealed the conidia arising from slightly tapering phialides. Furthermore, we differentiated these fungi as P.rubrigenum by Basic Local Alignment Search Tool (BLAST) algorithm. We performed surgical debridement of disseminated nodules and administered oral itraconazole for a duration of 4 weeks. One year after stopping itraconazole, there was no sign of relapsing subcutaneous nodules. To our knowledge, this is the third case report of PHM developing from skin infection by P. rubrigenum in human.
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spelling doaj.art-70514d46b3a94296aa7894e3fabbd1542022-12-21T19:00:07ZengKarger PublishersCase Reports in Dermatology1662-65672012-06-014211912410.1159/000339622339622Phaeohyphomycosis Caused by Phaeoacremoniumrubrigenum in an Immunosuppressive Patient: A Case Report and Review of the LiteratureSadanori FurudateShu SasaiYukikazu NumataTaku FujimuraSetsuya AibaPhaeohyphomycosis (PHM) is a rare, deep fungal infection of the skin and subcutaneous tissues caused by dematiaceous fungi. In this report, we describe a case of PHM caused by Phaeoacremoniumrubrigenum, which is generally known to infect woody plants. We detected the gray-blackish villi by biopsy culture material, and slide culture revealed the conidia arising from slightly tapering phialides. Furthermore, we differentiated these fungi as P.rubrigenum by Basic Local Alignment Search Tool (BLAST) algorithm. We performed surgical debridement of disseminated nodules and administered oral itraconazole for a duration of 4 weeks. One year after stopping itraconazole, there was no sign of relapsing subcutaneous nodules. To our knowledge, this is the third case report of PHM developing from skin infection by P. rubrigenum in human.http://www.karger.com/Article/FullText/339622PhaeohyphomycosisPhaeoacremoniumrubrigenumAdult Still’s disease
spellingShingle Sadanori Furudate
Shu Sasai
Yukikazu Numata
Taku Fujimura
Setsuya Aiba
Phaeohyphomycosis Caused by Phaeoacremoniumrubrigenum in an Immunosuppressive Patient: A Case Report and Review of the Literature
Case Reports in Dermatology
Phaeohyphomycosis
Phaeoacremoniumrubrigenum
Adult Still’s disease
title Phaeohyphomycosis Caused by Phaeoacremoniumrubrigenum in an Immunosuppressive Patient: A Case Report and Review of the Literature
title_full Phaeohyphomycosis Caused by Phaeoacremoniumrubrigenum in an Immunosuppressive Patient: A Case Report and Review of the Literature
title_fullStr Phaeohyphomycosis Caused by Phaeoacremoniumrubrigenum in an Immunosuppressive Patient: A Case Report and Review of the Literature
title_full_unstemmed Phaeohyphomycosis Caused by Phaeoacremoniumrubrigenum in an Immunosuppressive Patient: A Case Report and Review of the Literature
title_short Phaeohyphomycosis Caused by Phaeoacremoniumrubrigenum in an Immunosuppressive Patient: A Case Report and Review of the Literature
title_sort phaeohyphomycosis caused by phaeoacremoniumrubrigenum in an immunosuppressive patient a case report and review of the literature
topic Phaeohyphomycosis
Phaeoacremoniumrubrigenum
Adult Still’s disease
url http://www.karger.com/Article/FullText/339622
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