Phaeohyphomycosis Caused by Phaeoacremoniumrubrigenum in an Immunosuppressive Patient: A Case Report and Review of the Literature
Phaeohyphomycosis (PHM) is a rare, deep fungal infection of the skin and subcutaneous tissues caused by dematiaceous fungi. In this report, we describe a case of PHM caused by Phaeoacremoniumrubrigenum, which is generally known to infect woody plants. We detected the gray-blackish villi by biopsy cu...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Karger Publishers
2012-06-01
|
Series: | Case Reports in Dermatology |
Subjects: | |
Online Access: | http://www.karger.com/Article/FullText/339622 |
_version_ | 1819061463859331072 |
---|---|
author | Sadanori Furudate Shu Sasai Yukikazu Numata Taku Fujimura Setsuya Aiba |
author_facet | Sadanori Furudate Shu Sasai Yukikazu Numata Taku Fujimura Setsuya Aiba |
author_sort | Sadanori Furudate |
collection | DOAJ |
description | Phaeohyphomycosis (PHM) is a rare, deep fungal infection of the skin and subcutaneous tissues caused by dematiaceous fungi. In this report, we describe a case of PHM caused by Phaeoacremoniumrubrigenum, which is generally known to infect woody plants. We detected the gray-blackish villi by biopsy culture material, and slide culture revealed the conidia arising from slightly tapering phialides. Furthermore, we differentiated these fungi as P.rubrigenum by Basic Local Alignment Search Tool (BLAST) algorithm. We performed surgical debridement of disseminated nodules and administered oral itraconazole for a duration of 4 weeks. One year after stopping itraconazole, there was no sign of relapsing subcutaneous nodules. To our knowledge, this is the third case report of PHM developing from skin infection by P. rubrigenum in human. |
first_indexed | 2024-12-21T14:43:18Z |
format | Article |
id | doaj.art-70514d46b3a94296aa7894e3fabbd154 |
institution | Directory Open Access Journal |
issn | 1662-6567 |
language | English |
last_indexed | 2024-12-21T14:43:18Z |
publishDate | 2012-06-01 |
publisher | Karger Publishers |
record_format | Article |
series | Case Reports in Dermatology |
spelling | doaj.art-70514d46b3a94296aa7894e3fabbd1542022-12-21T19:00:07ZengKarger PublishersCase Reports in Dermatology1662-65672012-06-014211912410.1159/000339622339622Phaeohyphomycosis Caused by Phaeoacremoniumrubrigenum in an Immunosuppressive Patient: A Case Report and Review of the LiteratureSadanori FurudateShu SasaiYukikazu NumataTaku FujimuraSetsuya AibaPhaeohyphomycosis (PHM) is a rare, deep fungal infection of the skin and subcutaneous tissues caused by dematiaceous fungi. In this report, we describe a case of PHM caused by Phaeoacremoniumrubrigenum, which is generally known to infect woody plants. We detected the gray-blackish villi by biopsy culture material, and slide culture revealed the conidia arising from slightly tapering phialides. Furthermore, we differentiated these fungi as P.rubrigenum by Basic Local Alignment Search Tool (BLAST) algorithm. We performed surgical debridement of disseminated nodules and administered oral itraconazole for a duration of 4 weeks. One year after stopping itraconazole, there was no sign of relapsing subcutaneous nodules. To our knowledge, this is the third case report of PHM developing from skin infection by P. rubrigenum in human.http://www.karger.com/Article/FullText/339622PhaeohyphomycosisPhaeoacremoniumrubrigenumAdult Still’s disease |
spellingShingle | Sadanori Furudate Shu Sasai Yukikazu Numata Taku Fujimura Setsuya Aiba Phaeohyphomycosis Caused by Phaeoacremoniumrubrigenum in an Immunosuppressive Patient: A Case Report and Review of the Literature Case Reports in Dermatology Phaeohyphomycosis Phaeoacremoniumrubrigenum Adult Still’s disease |
title | Phaeohyphomycosis Caused by Phaeoacremoniumrubrigenum in an Immunosuppressive Patient: A Case Report and Review of the Literature |
title_full | Phaeohyphomycosis Caused by Phaeoacremoniumrubrigenum in an Immunosuppressive Patient: A Case Report and Review of the Literature |
title_fullStr | Phaeohyphomycosis Caused by Phaeoacremoniumrubrigenum in an Immunosuppressive Patient: A Case Report and Review of the Literature |
title_full_unstemmed | Phaeohyphomycosis Caused by Phaeoacremoniumrubrigenum in an Immunosuppressive Patient: A Case Report and Review of the Literature |
title_short | Phaeohyphomycosis Caused by Phaeoacremoniumrubrigenum in an Immunosuppressive Patient: A Case Report and Review of the Literature |
title_sort | phaeohyphomycosis caused by phaeoacremoniumrubrigenum in an immunosuppressive patient a case report and review of the literature |
topic | Phaeohyphomycosis Phaeoacremoniumrubrigenum Adult Still’s disease |
url | http://www.karger.com/Article/FullText/339622 |
work_keys_str_mv | AT sadanorifurudate phaeohyphomycosiscausedbyphaeoacremoniumrubrigenuminanimmunosuppressivepatientacasereportandreviewoftheliterature AT shusasai phaeohyphomycosiscausedbyphaeoacremoniumrubrigenuminanimmunosuppressivepatientacasereportandreviewoftheliterature AT yukikazunumata phaeohyphomycosiscausedbyphaeoacremoniumrubrigenuminanimmunosuppressivepatientacasereportandreviewoftheliterature AT takufujimura phaeohyphomycosiscausedbyphaeoacremoniumrubrigenuminanimmunosuppressivepatientacasereportandreviewoftheliterature AT setsuyaaiba phaeohyphomycosiscausedbyphaeoacremoniumrubrigenuminanimmunosuppressivepatientacasereportandreviewoftheliterature |