The Effects of a Digital, Transdiagnostic, Clinically and Peer-Moderated Treatment Platform for Young People With Emerging Mental Health Complaints: Repeated Measures Within-Subjects Study

BackgroundTo address the growing prevalence of youth mental health problems, early intervention is crucial to minimize individual, societal, and economic impacts. Indicative prevention aims to target emerging mental health complaints before the onset of a full-blown disorder....

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Main Authors: Marilon van Doorn, Anne Monsanto, Chen Lu Wang, Sander C J Verfaillie, Thérèse A M J van Amelsvoort, Arne Popma, Monique W M Jaspers, Ferko Öry, Mario Alvarez-Jimenez, John F Gleeson, Dorien H Nieman
Format: Article
Language:English
Published: JMIR Publications 2023-12-01
Series:JMIR mHealth and uHealth
Online Access:https://mhealth.jmir.org/2023/1/e50636
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author Marilon van Doorn
Anne Monsanto
Chen Lu Wang
Sander C J Verfaillie
Thérèse A M J van Amelsvoort
Arne Popma
Monique W M Jaspers
Ferko Öry
Mario Alvarez-Jimenez
John F Gleeson
Dorien H Nieman
author_facet Marilon van Doorn
Anne Monsanto
Chen Lu Wang
Sander C J Verfaillie
Thérèse A M J van Amelsvoort
Arne Popma
Monique W M Jaspers
Ferko Öry
Mario Alvarez-Jimenez
John F Gleeson
Dorien H Nieman
author_sort Marilon van Doorn
collection DOAJ
description BackgroundTo address the growing prevalence of youth mental health problems, early intervention is crucial to minimize individual, societal, and economic impacts. Indicative prevention aims to target emerging mental health complaints before the onset of a full-blown disorder. When intervening at this early stage, individuals are more responsive to treatment, resulting in cost-effective outcomes. The Moderated Online Social Therapy platform, which was successfully implemented and proven effective in Australia, is a digital, peer- and clinically moderated treatment platform designed for young people. The Netherlands was the first country outside Australia to implement this platform, under the name Engage Young People Early (ENYOY). It has the potential to reduce the likelihood of young people developing serious mental health disorders. ObjectiveThis study aims to investigate the effects on young people using the ENYOY-platform in relation to psychological distress, psychosocial functioning, and positive health parameters. MethodsDutch-speaking young people with emerging mental health complaints (N=131) participated in the ENYOY-platform for 6 months in a repeated measures within-subjects study. Psychological distress, psychosocial functioning, and positive health parameters were assessed at baseline and 3, 6, and 12 months. Repeated measures ANOVA was conducted and adjusted for age, sex, therapy, and community activity. The Reliable Change Index and Clinically Significant Index were computed to compare the baseline with the 6- and 12-month measurements. The missing data rate was 22.54% and the dropout rate 62.6% (82/131). ResultsThe primary analysis (77/131, 58.8%) showed that psychological distress decreased and psychosocial functioning improved over time with large effect sizes (P<.001 in both cases; ηp2=0.239 and 0.318, respectively) independent of age (P=.76 for psychological distress and P=.48 for psychosocial functioning), sex (P=.24 and P=.88, respectively), therapy activity (P=.49 and P=.80, respectively), or community activity (P=.59 and P=.48, respectively). Similarly, secondary analyses (51/131, 38.9%) showed significant effects of time on the quality of life, well-being, and meaningfulness positive health parameters (P<.05; ηp2=0.062, 0.140, and 0.121, respectively). Improvements in all outcome measures were found between baseline and 3 and 6 months (P≤.001-.01; d=0.23-0.62) and sustained at follow-up (P=.18-.97; d=0.01-0.16). The Reliable Change Index indicated psychological distress improvements in 38% (39/102) of cases, no change in 54.9% (56/102) of cases, and worsening in 5.9% (6/102) of cases. Regarding psychosocial functioning, the percentages were 50% (51/102), 43.1% (44/102), and 6.9% (7/102), respectively. The Clinically Significant Index demonstrated clinically significant changes in 75.5% (77/102) of cases for distress and 89.2% (91/102) for functioning. ConclusionsThis trial demonstrated that the ENYOY-platform holds promise as a transdiagnostic intervention for addressing emerging mental health complaints among young people in the Netherlands and laid the groundwork for further clinical research. It would be of great relevance to expand the population on and service delivery of the platform. International Registered Report Identifier (IRRID)RR2-10.1186/s12888-021-03315-x
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spelling doaj.art-70529c1ed36246be8a0ea57fef24929b2023-12-13T14:46:13ZengJMIR PublicationsJMIR mHealth and uHealth2291-52222023-12-0111e5063610.2196/50636The Effects of a Digital, Transdiagnostic, Clinically and Peer-Moderated Treatment Platform for Young People With Emerging Mental Health Complaints: Repeated Measures Within-Subjects StudyMarilon van Doornhttps://orcid.org/0000-0002-2396-0069Anne Monsantohttps://orcid.org/0009-0008-3849-6132Chen Lu Wanghttps://orcid.org/0009-0009-4427-1551Sander C J Verfailliehttps://orcid.org/0000-0003-1820-3378Thérèse A M J van Amelsvoorthttps://orcid.org/0000-0003-1135-5133Arne Popmahttps://orcid.org/0000-0003-2170-3023Monique W M Jaspershttps://orcid.org/0000-0001-8040-9153Ferko Öryhttps://orcid.org/0009-0004-1117-402XMario Alvarez-Jimenezhttps://orcid.org/0000-0002-3535-9086John F Gleesonhttps://orcid.org/0000-0001-7969-492XDorien H Niemanhttps://orcid.org/0000-0002-9846-4254 BackgroundTo address the growing prevalence of youth mental health problems, early intervention is crucial to minimize individual, societal, and economic impacts. Indicative prevention aims to target emerging mental health complaints before the onset of a full-blown disorder. When intervening at this early stage, individuals are more responsive to treatment, resulting in cost-effective outcomes. The Moderated Online Social Therapy platform, which was successfully implemented and proven effective in Australia, is a digital, peer- and clinically moderated treatment platform designed for young people. The Netherlands was the first country outside Australia to implement this platform, under the name Engage Young People Early (ENYOY). It has the potential to reduce the likelihood of young people developing serious mental health disorders. ObjectiveThis study aims to investigate the effects on young people using the ENYOY-platform in relation to psychological distress, psychosocial functioning, and positive health parameters. MethodsDutch-speaking young people with emerging mental health complaints (N=131) participated in the ENYOY-platform for 6 months in a repeated measures within-subjects study. Psychological distress, psychosocial functioning, and positive health parameters were assessed at baseline and 3, 6, and 12 months. Repeated measures ANOVA was conducted and adjusted for age, sex, therapy, and community activity. The Reliable Change Index and Clinically Significant Index were computed to compare the baseline with the 6- and 12-month measurements. The missing data rate was 22.54% and the dropout rate 62.6% (82/131). ResultsThe primary analysis (77/131, 58.8%) showed that psychological distress decreased and psychosocial functioning improved over time with large effect sizes (P<.001 in both cases; ηp2=0.239 and 0.318, respectively) independent of age (P=.76 for psychological distress and P=.48 for psychosocial functioning), sex (P=.24 and P=.88, respectively), therapy activity (P=.49 and P=.80, respectively), or community activity (P=.59 and P=.48, respectively). Similarly, secondary analyses (51/131, 38.9%) showed significant effects of time on the quality of life, well-being, and meaningfulness positive health parameters (P<.05; ηp2=0.062, 0.140, and 0.121, respectively). Improvements in all outcome measures were found between baseline and 3 and 6 months (P≤.001-.01; d=0.23-0.62) and sustained at follow-up (P=.18-.97; d=0.01-0.16). The Reliable Change Index indicated psychological distress improvements in 38% (39/102) of cases, no change in 54.9% (56/102) of cases, and worsening in 5.9% (6/102) of cases. Regarding psychosocial functioning, the percentages were 50% (51/102), 43.1% (44/102), and 6.9% (7/102), respectively. The Clinically Significant Index demonstrated clinically significant changes in 75.5% (77/102) of cases for distress and 89.2% (91/102) for functioning. ConclusionsThis trial demonstrated that the ENYOY-platform holds promise as a transdiagnostic intervention for addressing emerging mental health complaints among young people in the Netherlands and laid the groundwork for further clinical research. It would be of great relevance to expand the population on and service delivery of the platform. International Registered Report Identifier (IRRID)RR2-10.1186/s12888-021-03315-xhttps://mhealth.jmir.org/2023/1/e50636
spellingShingle Marilon van Doorn
Anne Monsanto
Chen Lu Wang
Sander C J Verfaillie
Thérèse A M J van Amelsvoort
Arne Popma
Monique W M Jaspers
Ferko Öry
Mario Alvarez-Jimenez
John F Gleeson
Dorien H Nieman
The Effects of a Digital, Transdiagnostic, Clinically and Peer-Moderated Treatment Platform for Young People With Emerging Mental Health Complaints: Repeated Measures Within-Subjects Study
JMIR mHealth and uHealth
title The Effects of a Digital, Transdiagnostic, Clinically and Peer-Moderated Treatment Platform for Young People With Emerging Mental Health Complaints: Repeated Measures Within-Subjects Study
title_full The Effects of a Digital, Transdiagnostic, Clinically and Peer-Moderated Treatment Platform for Young People With Emerging Mental Health Complaints: Repeated Measures Within-Subjects Study
title_fullStr The Effects of a Digital, Transdiagnostic, Clinically and Peer-Moderated Treatment Platform for Young People With Emerging Mental Health Complaints: Repeated Measures Within-Subjects Study
title_full_unstemmed The Effects of a Digital, Transdiagnostic, Clinically and Peer-Moderated Treatment Platform for Young People With Emerging Mental Health Complaints: Repeated Measures Within-Subjects Study
title_short The Effects of a Digital, Transdiagnostic, Clinically and Peer-Moderated Treatment Platform for Young People With Emerging Mental Health Complaints: Repeated Measures Within-Subjects Study
title_sort effects of a digital transdiagnostic clinically and peer moderated treatment platform for young people with emerging mental health complaints repeated measures within subjects study
url https://mhealth.jmir.org/2023/1/e50636
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