METHOD DEVELOPMENT AND VALIDATION FOR THE FLUOROQUINOLONES DETERMINATION BY STABILIZED SILVER NANOPARTICLES
Silver nanoparticles (AgNPs) stabilized with glutathione (GSH) were used as nanosensors for the determination of fluoroquinolones such as ciprofloxacin (CIP), norfloxacin (NOR) and enrofloxacin (ENRO) in aqueous systems. The AgNPs were stabilized with GSH (Ag-GSH NPs), whereas the decrease of the su...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Química
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| Series: | Química Nova |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422020000300271&lng=en&tlng=en |
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| author | Luiza D. de M. Moraes André F. de Oliveira Alvaro V. N. de C. Teixeira Renata P. Lopes |
| author_facet | Luiza D. de M. Moraes André F. de Oliveira Alvaro V. N. de C. Teixeira Renata P. Lopes |
| author_sort | Luiza D. de M. Moraes |
| collection | DOAJ |
| description | Silver nanoparticles (AgNPs) stabilized with glutathione (GSH) were used as nanosensors for the determination of fluoroquinolones such as ciprofloxacin (CIP), norfloxacin (NOR) and enrofloxacin (ENRO) in aqueous systems. The AgNPs were stabilized with GSH (Ag-GSH NPs), whereas the decrease of the surface plasmon resonance (SPR) band at 400 nm and the bathochromic shift of the absorption band were monitored. The method was validated and the analytical performance was verified. The results were satisfactory, with recoveries between 83.7 and 110% in almost all the experimental conditions and the repeatability and intermediate accuracy of less than 20%. The limits of detection were 0.397, 0.437 and 0.398 µmol L-1, and the limits of quantification were 1.203, 1.323 and 1.205 µmol L-1 for ciprofloxacin, norfloxacin and enrofloxacin, respectively. The method was selective in a group of drugs and applied in the determination of fluoroquinolones in potable water samples. |
| first_indexed | 2024-12-10T13:26:50Z |
| format | Article |
| id | doaj.art-70531edf25cf450483c8e45d7ee82a87 |
| institution | Directory Open Access Journal |
| issn | 0100-4042 1678-7064 |
| language | English |
| last_indexed | 2024-12-10T13:26:50Z |
| publisher | Sociedade Brasileira de Química |
| record_format | Article |
| series | Química Nova |
| spelling | doaj.art-70531edf25cf450483c8e45d7ee82a872022-12-22T01:47:07ZengSociedade Brasileira de QuímicaQuímica Nova0100-40421678-706443327127810.21577/0100-4042.20170484S0100-40422020000300271METHOD DEVELOPMENT AND VALIDATION FOR THE FLUOROQUINOLONES DETERMINATION BY STABILIZED SILVER NANOPARTICLESLuiza D. de M. MoraesAndré F. de OliveiraAlvaro V. N. de C. TeixeiraRenata P. LopesSilver nanoparticles (AgNPs) stabilized with glutathione (GSH) were used as nanosensors for the determination of fluoroquinolones such as ciprofloxacin (CIP), norfloxacin (NOR) and enrofloxacin (ENRO) in aqueous systems. The AgNPs were stabilized with GSH (Ag-GSH NPs), whereas the decrease of the surface plasmon resonance (SPR) band at 400 nm and the bathochromic shift of the absorption band were monitored. The method was validated and the analytical performance was verified. The results were satisfactory, with recoveries between 83.7 and 110% in almost all the experimental conditions and the repeatability and intermediate accuracy of less than 20%. The limits of detection were 0.397, 0.437 and 0.398 µmol L-1, and the limits of quantification were 1.203, 1.323 and 1.205 µmol L-1 for ciprofloxacin, norfloxacin and enrofloxacin, respectively. The method was selective in a group of drugs and applied in the determination of fluoroquinolones in potable water samples.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422020000300271&lng=en&tlng=ennanosensorssurface plasmonic resonancespectrophotometrydynamic light scattering |
| spellingShingle | Luiza D. de M. Moraes André F. de Oliveira Alvaro V. N. de C. Teixeira Renata P. Lopes METHOD DEVELOPMENT AND VALIDATION FOR THE FLUOROQUINOLONES DETERMINATION BY STABILIZED SILVER NANOPARTICLES Química Nova nanosensors surface plasmonic resonance spectrophotometry dynamic light scattering |
| title | METHOD DEVELOPMENT AND VALIDATION FOR THE FLUOROQUINOLONES DETERMINATION BY STABILIZED SILVER NANOPARTICLES |
| title_full | METHOD DEVELOPMENT AND VALIDATION FOR THE FLUOROQUINOLONES DETERMINATION BY STABILIZED SILVER NANOPARTICLES |
| title_fullStr | METHOD DEVELOPMENT AND VALIDATION FOR THE FLUOROQUINOLONES DETERMINATION BY STABILIZED SILVER NANOPARTICLES |
| title_full_unstemmed | METHOD DEVELOPMENT AND VALIDATION FOR THE FLUOROQUINOLONES DETERMINATION BY STABILIZED SILVER NANOPARTICLES |
| title_short | METHOD DEVELOPMENT AND VALIDATION FOR THE FLUOROQUINOLONES DETERMINATION BY STABILIZED SILVER NANOPARTICLES |
| title_sort | method development and validation for the fluoroquinolones determination by stabilized silver nanoparticles |
| topic | nanosensors surface plasmonic resonance spectrophotometry dynamic light scattering |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422020000300271&lng=en&tlng=en |
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