Network-based in silico drug efficacy screening
Attempts to predict novel use for existing drugs rarely consider information on the impact on the genes perturbed in a given disease. Here, the authors present a novel network-based drug-disease proximity measure that provides insight on gene specific therapeutic effect of drugs and may facilitate d...
Main Authors: | Emre Guney, Jörg Menche, Marc Vidal, Albert-László Barábasi |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2016-02-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms10331 |
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