Inflammatory Factors of Macular Atrophy in Eyes With Neovascular Age-Related Macular Degeneration Treated With Aflibercept

Inflammatory Factors of Macular Atrophy in Eyes With Neovascular Age-Related Macular Degeneration Treated With Aflibercept

BackgroundNeovascular age-related macular degeneration (nAMD) is a leading cause of blindness in older people. Low-grade inflammation is well-known as one of the pathogenic mechanisms in nAMD. Anti-vascular endothelial growth factor (VEGF) therapy is the first-line treatment for nAMD, although macul...

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Bibliographic Details
Main Authors: Tomohito Sato, Toshio Enoki, Yoko Karasawa, Hideaki Someya, Manzo Taguchi, Kozo Harimoto, Kei Takayama, Takayuki Kanda, Masataka Ito, Masaru Takeuchi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Immunology
Subjects:
aflibercept
aqueous humor cytokine
interferon-γ-inducible protein 10
macrophage inflammatory protein-1β
macular atrophy
monocyte chemoattractant protein-1
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.738521/full

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