Polygenic Control of Carotid Atherosclerosis in a BALB/cJ × SM/J Intercross and a Combined Cross Involving Multiple Mouse Strains

Polygenic Control of Carotid Atherosclerosis in a BALB/cJ × SM/J Intercross and a Combined Cross Involving Multiple Mouse Strains

Atherosclerosis in the carotid arteries is a major cause of ischemic stroke, which accounts for 85% of all stroke cases. Genetic factors contributing to carotid atherosclerosis remain poorly understood. The aim of this study was to identify chromosomal regions harboring genes contributing to carotid...

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Bibliographic Details
Main Authors: Andrew T. Grainger, Michael B. Jones, Mei-Hua Chen, Weibin Shi
Format: Article
Language:English
Published: Oxford University Press 2017-02-01
Series:G3: Genes, Genomes, Genetics
Subjects:
plaque
vessels
linkage mapping
haplotype analysis
dyslipidemia
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.116.037879

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