Refined high-content imaging-based phenotypic drug screening in zebrafish xenografts

Refined high-content imaging-based phenotypic drug screening in zebrafish xenografts

Abstract Zebrafish xenotransplantation models are increasingly applied for phenotypic drug screening to identify small compounds for precision oncology. Larval zebrafish xenografts offer the opportunity to perform drug screens at high-throughput in a complex in vivo environment. However, the full po...

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Bibliographic Details
Main Authors: C. Sturtzel, S. Grissenberger, P. Bozatzi, E. Scheuringer, A. Wenninger-Weinzierl, Z. Zajec, J. Dernovšek, S. Pascoal, V. Gehl, A. Kutsch, A. Granig, F. Rifatbegovic, M. Carre, A. Lang, I. Valtingojer, J. Moll, D. Lötsch, F. Erhart, G. Widhalm, D. Surdez, O. Delattre, N. André, J. Stampfl, T. Tomašič, S. Taschner-Mandl, M. Distel
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-023-00386-9

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