Camptothecin enhances the anti-tumor effect of low-dose apatinib combined with PD-1 inhibitor on hepatocellular carcinoma

Camptothecin enhances the anti-tumor effect of low-dose apatinib combined with PD-1 inhibitor on hepatocellular carcinoma

Abstract Apatinib has been shown to apply to a variety of solid tumors, including advanced hepatocellular carcinoma. Preclinical and preliminary clinical results confirmed the synergistic antitumor effects of apatinib in combination with anti-programmed death-1 (PD-1) inhibitors. In this study, we i...

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Bibliographic Details
Main Authors: Hankang Wang, Congcong Gao, Xiaodong Li, Feng Chen, Guijie Li
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Scientific Reports
Subjects:
Hepatocellular carcinoma
Camptothecin
Apatinib
PD-1 inhibitor
Nrf2
Online Access:https://doi.org/10.1038/s41598-024-57874-6

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