Human umbilical cord mesenchymal stem cell-derived exosomes promote microcirculation in aged diabetic mice by TGF-β1 signaling pathway

Human umbilical cord mesenchymal stem cell-derived exosomes promote microcirculation in aged diabetic mice by TGF-β1 signaling pathway

Abstract Background Microvascular dysfunction is one of the most common pathological characteristics in Type 2 diabetes. Human mesenchymal stem cell-derived exosomes (hUCMSCs-Exo) have diverse functions in improving microcirculation; however, the molecular mechanism of hUCMSCs-Exo in regulating burn...

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Bibliographic Details
Main Authors: Weijian Fan, Mengdie Zhou, Shaoqiu Zheng, Yang Liu, Songsong Pan, Peng Guo, Minjie Xu, Chao Hu, Anle Ding, Zan Wang, Shiwu Yin, Keqiang Zuo, Xiaoyun Xie
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Diabetology & Metabolic Syndrome
Subjects:
Diabetic peripheral angiopathy
Exosomes
CD105
TGF-β1
Microvascular
Online Access:https://doi.org/10.1186/s13098-023-01191-x

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