Low expression of CHRDL1 and SPARCL1 predicts poor prognosis of lung adenocarcinoma based on comprehensive analysis and immunohistochemical validation

Low expression of CHRDL1 and SPARCL1 predicts poor prognosis of lung adenocarcinoma based on comprehensive analysis and immunohistochemical validation

Abstract Purpose Exploring the molecular mechanisms of lung adenocarcinoma (LUAD) is beneficial for developing new therapeutic strategies and predicting prognosis. This study was performed to select core genes related to LUAD and to analyze their prognostic value. Methods Microarray datasets from th...

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Bibliographic Details
Main Authors: Huan Deng, Qingqing Hang, Dijian Shen, Yibi Zhang, Ming Chen
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Cancer Cell International
Subjects:
Lung adenocarcinoma
Weighted gene coexpression network analysis
Differential coexpression genes
Protein–protein interaction network
Survival analysis
Online Access:https://doi.org/10.1186/s12935-021-01933-9

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