Effects of concentration of amyloid β (Aβ) on viability of cultured retinal pigment epithelial cells

Effects of concentration of amyloid β (Aβ) on viability of cultured retinal pigment epithelial cells

Abstract Background Amyloid beta (Aβ) is a constituent of drusen that is a common sign of age-related macular degeneration (AMD). The purpose of this study was to investigate the effect of Aβ on human retinal pigment epithelial (RPE) cells in culture. Methods Cells from a human RPE cell line (ARPE-1...

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Bibliographic Details
Main Authors: Naonori Masuda, Hiroki Tsujinaka, Hiromasa Hirai, Mariko Yamashita, Tetsuo Ueda, Nahoko Ogata
Format: Article
Language:English
Published: BMC 2019-03-01
Series:BMC Ophthalmology
Subjects:
Age-related macular degeneration
Amyloid beta
Retinal pigment epithelial cells
Vascular endothelial growth factor
Pigment epithelium-derived factor
Receptor for advanced glycation end products
Online Access:http://link.springer.com/article/10.1186/s12886-019-1076-3

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http://link.springer.com/article/10.1186/s12886-019-1076-3

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