Feasibility of Low-Dose and Low-Contrast Media Volume Approach in Computed Tomography Cardiovascular Imaging Reconstructed with Model-Based Algorithm

<b>Aim</b>: To evaluate the dose reduction and image quality of low-dose, low-contrast media volume in computed tomography (CT) examinations reconstructed with the model-based iterative reconstruction (MBIR) algorithm in comparison with the hybrid iterative (HIR) one. <b>Methods:&l...

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Main Authors: Davide Ippolito, Marco Porta, Cesare Maino, Luca Riva, Maria Ragusi, Teresa Giandola, Paolo Niccolò Franco, Cecilia Cangiotti, Davide Gandola, Andrea De Vito, Cammillo Talei Franzesi, Rocco Corso
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Language:English
Published: MDPI AG 2024-02-01
Series:Tomography
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Online Access:https://www.mdpi.com/2379-139X/10/2/23
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author Davide Ippolito
Marco Porta
Cesare Maino
Luca Riva
Maria Ragusi
Teresa Giandola
Paolo Niccolò Franco
Cecilia Cangiotti
Davide Gandola
Andrea De Vito
Cammillo Talei Franzesi
Rocco Corso
author_facet Davide Ippolito
Marco Porta
Cesare Maino
Luca Riva
Maria Ragusi
Teresa Giandola
Paolo Niccolò Franco
Cecilia Cangiotti
Davide Gandola
Andrea De Vito
Cammillo Talei Franzesi
Rocco Corso
author_sort Davide Ippolito
collection DOAJ
description <b>Aim</b>: To evaluate the dose reduction and image quality of low-dose, low-contrast media volume in computed tomography (CT) examinations reconstructed with the model-based iterative reconstruction (MBIR) algorithm in comparison with the hybrid iterative (HIR) one. <b>Methods:</b> We prospectively enrolled a total of 401 patients referred for cardiovascular CT, evaluated with a 256-MDCT scan with a low kVp (80 kVp) reconstructed with an MBIR (study group) or a standard HIR protocol (100 kVp—control group) after injection of a fixed dose of contrast medium volume. Vessel contrast enhancement and image noise were measured by placing the region of interest (ROI) in the left ventricle, ascending aorta; left, right and circumflex coronary arteries; main, right and left pulmonary arteries; aortic arch; and abdominal aorta. The signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were computed. Subjective image quality obtained by consensus was assessed by using a 4-point Likert scale. Radiation dose exposure was recorded. <b>Results:</b> HU values of the proximal tract of all coronary arteries; main, right and left pulmonary arteries; and of the aorta were significantly higher in the study group than in the control group (<i>p</i> < 0.05), while the noise was significantly lower (<i>p</i> < 0.05). SNR and CNR values in all anatomic districts were significantly higher in the study group (<i>p</i> < 0.05). MBIR subjective image quality was significantly higher than HIR in CCTA and CTPA protocols (<i>p</i> < 0.05). Radiation dose was significantly lower in the study group (<i>p</i> < 0.05). <b>Conclusions:</b> The MBIR algorithm combined with low-kVp can help reduce radiation dose exposure, reduce noise, and increase objective and subjective image quality.
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spelling doaj.art-706e3181d2b44f6d85f8de2a1a6a4e812024-02-23T15:36:18ZengMDPI AGTomography2379-13812379-139X2024-02-0110228629810.3390/tomography10020023Feasibility of Low-Dose and Low-Contrast Media Volume Approach in Computed Tomography Cardiovascular Imaging Reconstructed with Model-Based AlgorithmDavide Ippolito0Marco Porta1Cesare Maino2Luca Riva3Maria Ragusi4Teresa Giandola5Paolo Niccolò Franco6Cecilia Cangiotti7Davide Gandola8Andrea De Vito9Cammillo Talei Franzesi10Rocco Corso11Departement of Medicine and Surgery, University of Milano-Bicocca, Piazza OMS 1, 20100 Milano, ItalyDepartment of Diagnostic Radiology, Fondazione IRCCS Fondazione San Gerardo dei Tintori, Via Pergolesi 33, 20900 Monza, ItalyDepartment of Diagnostic Radiology, Fondazione IRCCS Fondazione San Gerardo dei Tintori, Via Pergolesi 33, 20900 Monza, ItalyDepartment of Diagnostic Radiology, Fondazione IRCCS Fondazione San Gerardo dei Tintori, Via Pergolesi 33, 20900 Monza, ItalyDepartment of Diagnostic Radiology, Fondazione IRCCS Fondazione San Gerardo dei Tintori, Via Pergolesi 33, 20900 Monza, ItalyDepartment of Diagnostic Radiology, Fondazione IRCCS Fondazione San Gerardo dei Tintori, Via Pergolesi 33, 20900 Monza, ItalyDepartment of Diagnostic Radiology, Fondazione IRCCS Fondazione San Gerardo dei Tintori, Via Pergolesi 33, 20900 Monza, ItalyDepartment of Diagnostic Radiology, Fondazione IRCCS Fondazione San Gerardo dei Tintori, Via Pergolesi 33, 20900 Monza, ItalyDepartment of Diagnostic Radiology, Fondazione IRCCS Fondazione San Gerardo dei Tintori, Via Pergolesi 33, 20900 Monza, ItalyDepartment of Diagnostic Radiology, Fondazione IRCCS Fondazione San Gerardo dei Tintori, Via Pergolesi 33, 20900 Monza, ItalyDepartment of Diagnostic Radiology, Fondazione IRCCS Fondazione San Gerardo dei Tintori, Via Pergolesi 33, 20900 Monza, ItalyDepartment of Diagnostic Radiology, Fondazione IRCCS Fondazione San Gerardo dei Tintori, Via Pergolesi 33, 20900 Monza, Italy<b>Aim</b>: To evaluate the dose reduction and image quality of low-dose, low-contrast media volume in computed tomography (CT) examinations reconstructed with the model-based iterative reconstruction (MBIR) algorithm in comparison with the hybrid iterative (HIR) one. <b>Methods:</b> We prospectively enrolled a total of 401 patients referred for cardiovascular CT, evaluated with a 256-MDCT scan with a low kVp (80 kVp) reconstructed with an MBIR (study group) or a standard HIR protocol (100 kVp—control group) after injection of a fixed dose of contrast medium volume. Vessel contrast enhancement and image noise were measured by placing the region of interest (ROI) in the left ventricle, ascending aorta; left, right and circumflex coronary arteries; main, right and left pulmonary arteries; aortic arch; and abdominal aorta. The signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were computed. Subjective image quality obtained by consensus was assessed by using a 4-point Likert scale. Radiation dose exposure was recorded. <b>Results:</b> HU values of the proximal tract of all coronary arteries; main, right and left pulmonary arteries; and of the aorta were significantly higher in the study group than in the control group (<i>p</i> < 0.05), while the noise was significantly lower (<i>p</i> < 0.05). SNR and CNR values in all anatomic districts were significantly higher in the study group (<i>p</i> < 0.05). MBIR subjective image quality was significantly higher than HIR in CCTA and CTPA protocols (<i>p</i> < 0.05). Radiation dose was significantly lower in the study group (<i>p</i> < 0.05). <b>Conclusions:</b> The MBIR algorithm combined with low-kVp can help reduce radiation dose exposure, reduce noise, and increase objective and subjective image quality.https://www.mdpi.com/2379-139X/10/2/23radiation exposurealgorithmstomographyX-ray computedmodel-based iterative reconstructioncomputed tomography angiography
spellingShingle Davide Ippolito
Marco Porta
Cesare Maino
Luca Riva
Maria Ragusi
Teresa Giandola
Paolo Niccolò Franco
Cecilia Cangiotti
Davide Gandola
Andrea De Vito
Cammillo Talei Franzesi
Rocco Corso
Feasibility of Low-Dose and Low-Contrast Media Volume Approach in Computed Tomography Cardiovascular Imaging Reconstructed with Model-Based Algorithm
Tomography
radiation exposure
algorithms
tomography
X-ray computed
model-based iterative reconstruction
computed tomography angiography
title Feasibility of Low-Dose and Low-Contrast Media Volume Approach in Computed Tomography Cardiovascular Imaging Reconstructed with Model-Based Algorithm
title_full Feasibility of Low-Dose and Low-Contrast Media Volume Approach in Computed Tomography Cardiovascular Imaging Reconstructed with Model-Based Algorithm
title_fullStr Feasibility of Low-Dose and Low-Contrast Media Volume Approach in Computed Tomography Cardiovascular Imaging Reconstructed with Model-Based Algorithm
title_full_unstemmed Feasibility of Low-Dose and Low-Contrast Media Volume Approach in Computed Tomography Cardiovascular Imaging Reconstructed with Model-Based Algorithm
title_short Feasibility of Low-Dose and Low-Contrast Media Volume Approach in Computed Tomography Cardiovascular Imaging Reconstructed with Model-Based Algorithm
title_sort feasibility of low dose and low contrast media volume approach in computed tomography cardiovascular imaging reconstructed with model based algorithm
topic radiation exposure
algorithms
tomography
X-ray computed
model-based iterative reconstruction
computed tomography angiography
url https://www.mdpi.com/2379-139X/10/2/23
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