Orbivirus NS4 Proteins Play Multiple Roles to Dampen Cellular Responses

Orbivirus NS4 Proteins Play Multiple Roles to Dampen Cellular Responses

Non-structural protein 4 (NS4) of insect-borne and tick-borne orbiviruses is encoded by genome segment 9, from a secondary open reading frame. Though a protein dispensable for bluetongue virus (BTV) replication, it has been shown to counter the interferon response in cells infected with BTV or Afric...

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Bibliographic Details
Main Authors: Fauziah Mohd Jaafar, Mourad Belhouchet, Baptiste Monsion, Lesley Bell-Sakyi, Peter P. C. Mertens, Houssam Attoui
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Viruses
Subjects:
orbivirus
bluetongue virus
Great Island virus
St. Croix River virus
NS4
innate responses
Online Access:https://www.mdpi.com/1999-4915/15/9/1908

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