Red blood cell glutathione peroxidase activity in female nulligravid and pregnant rats
<p>Abstract</p> <p>Background</p> <p>The alterations of the glutathione peroxidase enzyme complex system occur in physiological conditions such as aging and oxidative stress consequent to strenuous exercise.</p> <p>Methods</p> <p>Authors optimize...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2009-01-01
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| Series: | Reproductive Biology and Endocrinology |
| Online Access: | http://www.rbej.com/content/7/1/7 |
| _version_ | 1818524938109190144 |
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| author | Martino Guglielmo Gallo Giuseppe |
| author_facet | Martino Guglielmo Gallo Giuseppe |
| author_sort | Martino Guglielmo |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>The alterations of the glutathione peroxidase enzyme complex system occur in physiological conditions such as aging and oxidative stress consequent to strenuous exercise.</p> <p>Methods</p> <p>Authors optimize the spectrophotometric method to measure glutathione peroxidase activity in rat red blood cell membranes.</p> <p>Results</p> <p>The optimization, when applied to age paired rats, both nulligravid and pregnant, shows that pregnancy induces, at seventeen d of pregnancy, an increase of both reactive oxygen substance concentration in red blood cells and membrane glutathione peroxidase activity.</p> <p>Conclusion</p> <p>The glutathione peroxidase increase in erythrocyte membranes is induced by systemic oxidative stress long lasting rat pregnancy.</p> |
| first_indexed | 2024-12-11T06:03:17Z |
| format | Article |
| id | doaj.art-70772c77031e498391434a91068676be |
| institution | Directory Open Access Journal |
| issn | 1477-7827 |
| language | English |
| last_indexed | 2024-12-11T06:03:17Z |
| publishDate | 2009-01-01 |
| publisher | BMC |
| record_format | Article |
| series | Reproductive Biology and Endocrinology |
| spelling | doaj.art-70772c77031e498391434a91068676be2022-12-22T01:18:23ZengBMCReproductive Biology and Endocrinology1477-78272009-01-0171710.1186/1477-7827-7-7Red blood cell glutathione peroxidase activity in female nulligravid and pregnant ratsMartino GuglielmoGallo Giuseppe<p>Abstract</p> <p>Background</p> <p>The alterations of the glutathione peroxidase enzyme complex system occur in physiological conditions such as aging and oxidative stress consequent to strenuous exercise.</p> <p>Methods</p> <p>Authors optimize the spectrophotometric method to measure glutathione peroxidase activity in rat red blood cell membranes.</p> <p>Results</p> <p>The optimization, when applied to age paired rats, both nulligravid and pregnant, shows that pregnancy induces, at seventeen d of pregnancy, an increase of both reactive oxygen substance concentration in red blood cells and membrane glutathione peroxidase activity.</p> <p>Conclusion</p> <p>The glutathione peroxidase increase in erythrocyte membranes is induced by systemic oxidative stress long lasting rat pregnancy.</p>http://www.rbej.com/content/7/1/7 |
| spellingShingle | Martino Guglielmo Gallo Giuseppe Red blood cell glutathione peroxidase activity in female nulligravid and pregnant rats Reproductive Biology and Endocrinology |
| title | Red blood cell glutathione peroxidase activity in female nulligravid and pregnant rats |
| title_full | Red blood cell glutathione peroxidase activity in female nulligravid and pregnant rats |
| title_fullStr | Red blood cell glutathione peroxidase activity in female nulligravid and pregnant rats |
| title_full_unstemmed | Red blood cell glutathione peroxidase activity in female nulligravid and pregnant rats |
| title_short | Red blood cell glutathione peroxidase activity in female nulligravid and pregnant rats |
| title_sort | red blood cell glutathione peroxidase activity in female nulligravid and pregnant rats |
| url | http://www.rbej.com/content/7/1/7 |
| work_keys_str_mv | AT martinoguglielmo redbloodcellglutathioneperoxidaseactivityinfemalenulligravidandpregnantrats AT gallogiuseppe redbloodcellglutathioneperoxidaseactivityinfemalenulligravidandpregnantrats |