A tissue-like platform for studying engineered quiescent human T-cells’ interactions with dendritic cells

Research in the field of human immunology is restricted by the lack of a system that reconstitutes the in-situactivation dynamics of quiescent human antigen-specific T-cells interacting with dendritic cells. Here we report a tissue-like system that recapitulates the dynamics of engineered primary hu...

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Bibliographic Details
Main Authors: Enas Abu-Shah, Philippos Demetriou, Štefan Bálint, Viveka Mayya, Mikhail A Kutuzov, Omer Dushek, Michael L Dustin
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-09-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/48221