Selecting chemotherapy schedules for adjuvant treatment of early stage breast cancer, what is the rationale behind?

Breast cancer is one of the most prevalent cancers that oncologists are faced with in their clinics. The varieties of clinical features of the disease result to very different scenarios in the processes of treatment decision making. While classic factors of stage, grade, age and hormone receptor sta...

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Main Authors: Roham Salek, Narges Bayat Mokhtari, Soudabeh Shahidsales
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2015-07-01
Series:Reviews in Clinical Medicine
Subjects:
Online Access:https://rcm.mums.ac.ir/article_4340_0ef7790a2fa010c913be579434a91ec6.pdf
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author Roham Salek
Narges Bayat Mokhtari
Soudabeh Shahidsales
author_facet Roham Salek
Narges Bayat Mokhtari
Soudabeh Shahidsales
author_sort Roham Salek
collection DOAJ
description Breast cancer is one of the most prevalent cancers that oncologists are faced with in their clinics. The varieties of clinical features of the disease result to very different scenarios in the processes of treatment decision making. While classic factors of stage, grade, age and hormone receptor status are still the criterion for choosing treatment, a very delicate list of other prognostic and predictive factors have been entered to this field over recent two decades. The evidence-based medicine rules to treat patients based on the best evidences that have been found by powered randomized clinical trials. Different panels and guidelines gathering these evidences try to help oncologists to find the best treatment methods through the variable and sometimes contradicting results. As it is always the main objective, increasing the survival rates in addition to the ideal aim of curing the disease is usually the target.  Finding the best and the most practical chemotherapy regimen against breast cancer needs to notice the biology of this disease and its varieties along with each individual patient condition. It is clear that not all patients need the most complicated and expensive treatment.
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spelling doaj.art-707a2c64de544577b577ddcdb9d488332022-12-27T13:12:29ZengMashhad University of Medical SciencesReviews in Clinical Medicine2345-62562345-68922015-07-012312913410.17463/RCM.2015.03.0054340Selecting chemotherapy schedules for adjuvant treatment of early stage breast cancer, what is the rationale behind?Roham Salek0Narges Bayat Mokhtari1Soudabeh Shahidsales2Cancer Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.Cancer Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.Cancer Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.Breast cancer is one of the most prevalent cancers that oncologists are faced with in their clinics. The varieties of clinical features of the disease result to very different scenarios in the processes of treatment decision making. While classic factors of stage, grade, age and hormone receptor status are still the criterion for choosing treatment, a very delicate list of other prognostic and predictive factors have been entered to this field over recent two decades. The evidence-based medicine rules to treat patients based on the best evidences that have been found by powered randomized clinical trials. Different panels and guidelines gathering these evidences try to help oncologists to find the best treatment methods through the variable and sometimes contradicting results. As it is always the main objective, increasing the survival rates in addition to the ideal aim of curing the disease is usually the target.  Finding the best and the most practical chemotherapy regimen against breast cancer needs to notice the biology of this disease and its varieties along with each individual patient condition. It is clear that not all patients need the most complicated and expensive treatment.https://rcm.mums.ac.ir/article_4340_0ef7790a2fa010c913be579434a91ec6.pdfadjuvant treatmentchemotherapy schedulesearly stage breast cancer
spellingShingle Roham Salek
Narges Bayat Mokhtari
Soudabeh Shahidsales
Selecting chemotherapy schedules for adjuvant treatment of early stage breast cancer, what is the rationale behind?
Reviews in Clinical Medicine
adjuvant treatment
chemotherapy schedules
early stage breast cancer
title Selecting chemotherapy schedules for adjuvant treatment of early stage breast cancer, what is the rationale behind?
title_full Selecting chemotherapy schedules for adjuvant treatment of early stage breast cancer, what is the rationale behind?
title_fullStr Selecting chemotherapy schedules for adjuvant treatment of early stage breast cancer, what is the rationale behind?
title_full_unstemmed Selecting chemotherapy schedules for adjuvant treatment of early stage breast cancer, what is the rationale behind?
title_short Selecting chemotherapy schedules for adjuvant treatment of early stage breast cancer, what is the rationale behind?
title_sort selecting chemotherapy schedules for adjuvant treatment of early stage breast cancer what is the rationale behind
topic adjuvant treatment
chemotherapy schedules
early stage breast cancer
url https://rcm.mums.ac.ir/article_4340_0ef7790a2fa010c913be579434a91ec6.pdf
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AT soudabehshahidsales selectingchemotherapyschedulesforadjuvanttreatmentofearlystagebreastcancerwhatistherationalebehind