Thioredoxin and glutaredoxin regulate metabolism through different multiplex thiol switches

Thioredoxin and glutaredoxin regulate metabolism through different multiplex thiol switches

The aim of the present study was to define the role of Trx and Grx on metabolic thiol redox regulation and identify their protein and metabolite targets. The hepatocarcinoma-derived HepG2 cell line under both normal and oxidative/nitrosative conditions by overexpression of NO synthase (NOS3) was use...

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Bibliographic Details
Main Authors:	MJ López-Grueso, R González-Ojeda, R Requejo-Aguilar, B McDonagh, CA Fuentes-Almagro, J. Muntané, J.A. Bárcena, CA Padilla
Format:	Article
Language:	English
Published:	Elsevier 2019-02-01
Series:	Redox Biology
Online Access:	http://www.sciencedirect.com/science/article/pii/S2213231718309170

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