The Effect of Drug Heterogeneous Distributions within Core-Sheath Nanostructures on Its Sustained Release Profiles

The Effect of Drug Heterogeneous Distributions within Core-Sheath Nanostructures on Its Sustained Release Profiles

The sustained release of a water-soluble drug is always a key and important issue in pharmaceutics. In this study, using cellulose acetate (CA) as a biomacromolecular matrix, core-sheath nanofibers were developed for providing a sustained release of a model drug—metformin hydrochloride (MET). The co...

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Bibliographic Details
Main Authors: Haixia Xu, Xizi Xu, Siyu Li, Wen-Liang Song, Deng-Guang Yu, S. W. Annie Bligh
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Biomolecules
Subjects:
sustained release
water-soluble drug
core–sheath structures
triaxial electrospinning
cellulose acetate
metformin hydrochloride
Online Access:https://www.mdpi.com/2218-273X/11/9/1330

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