Invasions by Eurasian Avian Influenza Virus H6 Genes and Replacement of Its North American Clade
The spread of highly pathogenic avian influenza virus (AIV) (H5N1) underlines the potential for global AIV movement through birds. The phylogenies of AIV genes from avian hosts usually separate into Eurasian and North American clades, reflecting limited bird migration between the hemispheres. Howeve...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Centers for Disease Control and Prevention
2009-07-01
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| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/15/7/09-0245_article |
| _version_ | 1818671345796382720 |
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| author | Heinrich zu Dohna Jinling Li Carol J. Cardona Joy Miller Tim E. Carpenter |
| author_facet | Heinrich zu Dohna Jinling Li Carol J. Cardona Joy Miller Tim E. Carpenter |
| author_sort | Heinrich zu Dohna |
| collection | DOAJ |
| description | The spread of highly pathogenic avian influenza virus (AIV) (H5N1) underlines the potential for global AIV movement through birds. The phylogenies of AIV genes from avian hosts usually separate into Eurasian and North American clades, reflecting limited bird migration between the hemispheres. However, mounting evidence that some H6 sequences from North America cluster with Eurasian subtype H6 sequences calls the strict hemispheric divide into question. We conducted a comprehensive phylogenetic analysis of the extent and timing of cross-hemisphere movements by the H6 gene. Results suggested that Eurasian H6 subtype has invaded North America several times, with the first invasions occurring 10 years before the first detection of invading isolates. The members of the North American clade decreased from 100% in the 1980s to 20% in the 2000s among H6 isolates from North America. Unraveling the reasons for this large-scale gene movement between hemispheres might identify drivers of global AIV circulation. |
| first_indexed | 2024-12-17T07:22:32Z |
| format | Article |
| id | doaj.art-707dcdf2b0f84334a8a5b60c9ebfed97 |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-12-17T07:22:32Z |
| publishDate | 2009-07-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-707dcdf2b0f84334a8a5b60c9ebfed972022-12-21T21:58:43ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592009-07-011571040104510.3201/eid1507.090245Invasions by Eurasian Avian Influenza Virus H6 Genes and Replacement of Its North American CladeHeinrich zu DohnaJinling LiCarol J. CardonaJoy MillerTim E. CarpenterThe spread of highly pathogenic avian influenza virus (AIV) (H5N1) underlines the potential for global AIV movement through birds. The phylogenies of AIV genes from avian hosts usually separate into Eurasian and North American clades, reflecting limited bird migration between the hemispheres. However, mounting evidence that some H6 sequences from North America cluster with Eurasian subtype H6 sequences calls the strict hemispheric divide into question. We conducted a comprehensive phylogenetic analysis of the extent and timing of cross-hemisphere movements by the H6 gene. Results suggested that Eurasian H6 subtype has invaded North America several times, with the first invasions occurring 10 years before the first detection of invading isolates. The members of the North American clade decreased from 100% in the 1980s to 20% in the 2000s among H6 isolates from North America. Unraveling the reasons for this large-scale gene movement between hemispheres might identify drivers of global AIV circulation.https://wwwnc.cdc.gov/eid/article/15/7/09-0245_articleH6phylogenyEurasiaNorth Americahemisphereinfluenza |
| spellingShingle | Heinrich zu Dohna Jinling Li Carol J. Cardona Joy Miller Tim E. Carpenter Invasions by Eurasian Avian Influenza Virus H6 Genes and Replacement of Its North American Clade Emerging Infectious Diseases H6 phylogeny Eurasia North America hemisphere influenza |
| title | Invasions by Eurasian Avian Influenza Virus H6 Genes and Replacement of Its North American Clade |
| title_full | Invasions by Eurasian Avian Influenza Virus H6 Genes and Replacement of Its North American Clade |
| title_fullStr | Invasions by Eurasian Avian Influenza Virus H6 Genes and Replacement of Its North American Clade |
| title_full_unstemmed | Invasions by Eurasian Avian Influenza Virus H6 Genes and Replacement of Its North American Clade |
| title_short | Invasions by Eurasian Avian Influenza Virus H6 Genes and Replacement of Its North American Clade |
| title_sort | invasions by eurasian avian influenza virus h6 genes and replacement of its north american clade |
| topic | H6 phylogeny Eurasia North America hemisphere influenza |
| url | https://wwwnc.cdc.gov/eid/article/15/7/09-0245_article |
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