Molecular heterogeneity in malignant peripheral nerve sheath tumors associated with neurofibromatosis type 1

Molecular heterogeneity in malignant peripheral nerve sheath tumors associated with neurofibromatosis type 1

<p>Abstract</p> <p>Neurofibromatosis type-1 (NF1), resulting from <it>NF1</it> gene loss of function, is characterized by an increased risk of developing benign and malignant peripheral nerve sheath tumors (MPNSTs). Whereas the cellular heterogeneity of NF1-associated t...

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Bibliographic Details
Main Authors: Thomas Laura, Mautner Victor-Felix, Cooper David N, Upadhyaya Meena
Format: Article
Language:English
Published: BMC 2012-09-01
Series:Human Genomics
Subjects:
Neurofibromatosis type 1
Malignant peripheral nerve sheath tumors
Molecular heterogeneity
<it>TP53</it>
Online Access:http://www.humgenomics.com/content/6/1/18

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