Frailty index as a clinical measure of biological age in psychiatry
The concepts of “accelerated biological ageing” and “premature biological senescence” have been receiving increasing attention in relation to psychiatric diseases, with clinical, epidemiological and molecular observations suggesting that psychopathological processes can have significant relationship...
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| Format: | Article |
| Language: | English |
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Cambridge University Press
2021-04-01
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| Series: | European Psychiatry |
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| Online Access: | https://www.cambridge.org/core/product/identifier/S0924933821001978/type/journal_article |
| _version_ | 1797616439496015872 |
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| author | F.S. Bersani |
| author_facet | F.S. Bersani |
| author_sort | F.S. Bersani |
| collection | DOAJ |
| description | The concepts of “accelerated biological ageing” and “premature biological senescence” have been receiving increasing attention in relation to psychiatric diseases, with clinical, epidemiological and molecular observations suggesting that psychopathological processes can have significant relationships with aging-related phenomena. The deficit accumulation model postulates that the individual’s biological age and functional status is related to the amount of health deficits accumulated over time and that one’s biological age can be estimated by summarizing health deficits in a single continuous variable, the so-called “frailty index” (FI). In this presentation it will be discussed the possibility that the FI, which condenses information arising from multidimensional evaluations, represents a potential clinically-useful macroscopic indicator of biological age which can add relevant information to the measurements currently implemented in the study of accelerated biological age in psychiatric diseases. |
| first_indexed | 2024-03-11T07:41:11Z |
| format | Article |
| id | doaj.art-708008cf9727412bb03c8a15cc739ec4 |
| institution | Directory Open Access Journal |
| issn | 0924-9338 1778-3585 |
| language | English |
| last_indexed | 2024-03-11T07:41:11Z |
| publishDate | 2021-04-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | European Psychiatry |
| spelling | doaj.art-708008cf9727412bb03c8a15cc739ec42023-11-17T05:08:31ZengCambridge University PressEuropean Psychiatry0924-93381778-35852021-04-0164S63S6310.1192/j.eurpsy.2021.197Frailty index as a clinical measure of biological age in psychiatryF.S. Bersani0Department Of Human Neurosciences, Sapienza University of Rome, Rome, ItalyThe concepts of “accelerated biological ageing” and “premature biological senescence” have been receiving increasing attention in relation to psychiatric diseases, with clinical, epidemiological and molecular observations suggesting that psychopathological processes can have significant relationships with aging-related phenomena. The deficit accumulation model postulates that the individual’s biological age and functional status is related to the amount of health deficits accumulated over time and that one’s biological age can be estimated by summarizing health deficits in a single continuous variable, the so-called “frailty index” (FI). In this presentation it will be discussed the possibility that the FI, which condenses information arising from multidimensional evaluations, represents a potential clinically-useful macroscopic indicator of biological age which can add relevant information to the measurements currently implemented in the study of accelerated biological age in psychiatric diseases.https://www.cambridge.org/core/product/identifier/S0924933821001978/type/journal_articlecomorbidityaccelerated biological agingfrailty indexdeficit accumulation model |
| spellingShingle | F.S. Bersani Frailty index as a clinical measure of biological age in psychiatry European Psychiatry comorbidity accelerated biological aging frailty index deficit accumulation model |
| title | Frailty index as a clinical measure of biological age in psychiatry |
| title_full | Frailty index as a clinical measure of biological age in psychiatry |
| title_fullStr | Frailty index as a clinical measure of biological age in psychiatry |
| title_full_unstemmed | Frailty index as a clinical measure of biological age in psychiatry |
| title_short | Frailty index as a clinical measure of biological age in psychiatry |
| title_sort | frailty index as a clinical measure of biological age in psychiatry |
| topic | comorbidity accelerated biological aging frailty index deficit accumulation model |
| url | https://www.cambridge.org/core/product/identifier/S0924933821001978/type/journal_article |
| work_keys_str_mv | AT fsbersani frailtyindexasaclinicalmeasureofbiologicalageinpsychiatry |