A Metabolomics-Based Study on the Discriminative Classification Models and Toxicological Mechanism of Estazolam Fatal Intoxication

A Metabolomics-Based Study on the Discriminative Classification Models and Toxicological Mechanism of Estazolam Fatal Intoxication

Fatal intoxication with sedative-hypnotic drugs is increasing yearly. However, the plasma drug concentration data for fatal intoxication involving these substances are not systematic and even overlap with the intoxication group. Therefore, developing a more precise and trustworthy approach to determ...

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Bibliographic Details
Main Authors: Xiaohui Dai, Rui Bai, Bing Xie, Jiahong Xiang, Xingang Miao, Yan Shi, Feng Yu, Bin Cong, Di Wen, Chunling Ma
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Metabolites
Subjects:
estazolam
fatal intoxication
metabolomic
LC-MS
mechanism validation
Online Access:https://www.mdpi.com/2218-1989/13/4/567

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