Jedi-1/MEGF12-mediated phagocytosis controls the pro-neurogenic properties of microglia in the ventricular-subventricular zone

Summary: Microglia are the primary phagocytes in the central nervous system and clear dead cells generated during development or disease. The phagocytic process shapes the microglia phenotype, which affects the local environment. A unique population of microglia resides in the ventricular-subventric...

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Main Authors: Vivianne Morrison, Matthew Houpert, Jonathan Trapani, Asa Brockman, Philip Kingsley, Ketaki Katdare, Hillary Layden, Gabriela Nguena-Jones, Alexandra Trevisan, Kathleen Maguire-Zeiss, Lawrence Marnett, Gregory Bix, Rebecca Ihrie, Bruce Carter
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723014353