In vivo expression technology identifies a novel virulence factor critical for Borrelia burgdorferi persistence in mice.

In vivo expression technology identifies a novel virulence factor critical for Borrelia burgdorferi persistence in mice.

Analysis of the transcriptome of Borrelia burgdorferi, the causative agent of Lyme disease, during infection has proven difficult due to the low spirochete loads in the mammalian tissues. To overcome this challenge, we have developed an In Vivo Expression Technology (IVET) system for identification...

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Bibliographic Details
Main Authors: Tisha Choudhury Ellis, Sunny Jain, Angelika K Linowski, Kelli Rike, Aaron Bestor, Patricia A Rosa, Micah Halpern, Stephanie Kurhanewicz, Mollie W Jewett
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3757035?pdf=render

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