Management of cryptorchidism in adolescent and adult males

Abstract Background In developing countries, it is not unusual for patients with undescended testes (UDT) to present in adulthood and the late detection of UDT can be problematic. The limited contribution to fertility and increased potential of malignancy seen in UDT have swayed many authors towards...

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Main Authors: J. T. Viljoen, A. Zarrabi, A. Van der Merwe
Format: Article
Language:English
Published: SpringerOpen 2020-09-01
Series:African Journal of Urology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12301-020-00051-8
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author J. T. Viljoen
A. Zarrabi
A. Van der Merwe
author_facet J. T. Viljoen
A. Zarrabi
A. Van der Merwe
author_sort J. T. Viljoen
collection DOAJ
description Abstract Background In developing countries, it is not unusual for patients with undescended testes (UDT) to present in adulthood and the late detection of UDT can be problematic. The limited contribution to fertility and increased potential of malignancy seen in UDT have swayed many authors towards recommending orchidectomy, rather than orchidopexy, for the adult patient presenting with cryptorchidism. With conflicting data, and most guidelines aimed at first world countries with pre-pubertal patients as their focus group, a lot of uncertainty exists regarding the management of adults who present with cryptorchidism. This may result in variation in the approach to management of this patient population. Methods A retrospective review was conducted of patients with cryptorchidism, aged 12 years or older at the time of surgery. The following data were retrieved: patient’s age, medical and previous surgical history, clinical features of UDT (laterality, position and size), date of surgery, intra-operative findings and procedure performed. Management decisions were compared to the most recent guidelines. Results The mean age of the 106 subjects was 25.4 years. An orchidectomy was performed in a total of 30 (24.2%) of the 124 testicular units. The majority of testes, 91 (73.4%), in this group were preserved. Of these, 43 (47.3%) were older than 18 years of age, 33 (36.2%) were reported as having unilateral UDT with a normal contralateral testis and in 9 (9.8%) of these cases, the preserved testes were described as being atrophic. The majority (59.7%) of UDT in the post-pubertal group (> 18 years) were managed by orchidopexy. Conclusion Contrary to the recommended treatment for this group of patients, there was a general tendency towards testicular preservation. The decision on surgical management was made by the attending surgical team. This not only demonstrates variation in the management of UDT, but could also be a reflection of the lack of sufficient guidelines as to the management of the post-pubertal patient presenting with UDT. Further studies, following cryptorchidism through adulthood, are needed to refine guidelines for the optimal management of this group of patients.
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spelling doaj.art-708c0f38de634dd194856754c0c27f3a2022-12-22T01:12:04ZengSpringerOpenAfrican Journal of Urology1110-57041961-99872020-09-012611610.1186/s12301-020-00051-8Management of cryptorchidism in adolescent and adult malesJ. T. Viljoen0A. Zarrabi1A. Van der Merwe22Military HospitalDepartment of Urology, Faculty of Health Sciences, Stellenbosch UniversityDepartment of Urology, Faculty of Health Sciences, Stellenbosch UniversityAbstract Background In developing countries, it is not unusual for patients with undescended testes (UDT) to present in adulthood and the late detection of UDT can be problematic. The limited contribution to fertility and increased potential of malignancy seen in UDT have swayed many authors towards recommending orchidectomy, rather than orchidopexy, for the adult patient presenting with cryptorchidism. With conflicting data, and most guidelines aimed at first world countries with pre-pubertal patients as their focus group, a lot of uncertainty exists regarding the management of adults who present with cryptorchidism. This may result in variation in the approach to management of this patient population. Methods A retrospective review was conducted of patients with cryptorchidism, aged 12 years or older at the time of surgery. The following data were retrieved: patient’s age, medical and previous surgical history, clinical features of UDT (laterality, position and size), date of surgery, intra-operative findings and procedure performed. Management decisions were compared to the most recent guidelines. Results The mean age of the 106 subjects was 25.4 years. An orchidectomy was performed in a total of 30 (24.2%) of the 124 testicular units. The majority of testes, 91 (73.4%), in this group were preserved. Of these, 43 (47.3%) were older than 18 years of age, 33 (36.2%) were reported as having unilateral UDT with a normal contralateral testis and in 9 (9.8%) of these cases, the preserved testes were described as being atrophic. The majority (59.7%) of UDT in the post-pubertal group (> 18 years) were managed by orchidopexy. Conclusion Contrary to the recommended treatment for this group of patients, there was a general tendency towards testicular preservation. The decision on surgical management was made by the attending surgical team. This not only demonstrates variation in the management of UDT, but could also be a reflection of the lack of sufficient guidelines as to the management of the post-pubertal patient presenting with UDT. Further studies, following cryptorchidism through adulthood, are needed to refine guidelines for the optimal management of this group of patients.http://link.springer.com/article/10.1186/s12301-020-00051-8Undescended testisCryptorchidismOrchidopexyOrchidectomyAdultAdolescent
spellingShingle J. T. Viljoen
A. Zarrabi
A. Van der Merwe
Management of cryptorchidism in adolescent and adult males
African Journal of Urology
Undescended testis
Cryptorchidism
Orchidopexy
Orchidectomy
Adult
Adolescent
title Management of cryptorchidism in adolescent and adult males
title_full Management of cryptorchidism in adolescent and adult males
title_fullStr Management of cryptorchidism in adolescent and adult males
title_full_unstemmed Management of cryptorchidism in adolescent and adult males
title_short Management of cryptorchidism in adolescent and adult males
title_sort management of cryptorchidism in adolescent and adult males
topic Undescended testis
Cryptorchidism
Orchidopexy
Orchidectomy
Adult
Adolescent
url http://link.springer.com/article/10.1186/s12301-020-00051-8
work_keys_str_mv AT jtviljoen managementofcryptorchidisminadolescentandadultmales
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