Dietary Grape Seed Proanthocyanidin Alleviates the Liver Injury Induced by Long-Term High-Fat Diets in Sprague Dawley Rats

Dietary Grape Seed Proanthocyanidin Alleviates the Liver Injury Induced by Long-Term High-Fat Diets in Sprague Dawley Rats

In mammals, the liver is the most important organ that plays a vital function in lipid metabolism. Grape seed proanthocyanidin (GSPE) is a kind of natural polyphenolic compound primarily obtained from grape skin and seeds. Recent research found it had high bioavailability in defending against obesit...

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Bibliographic Details
Main Authors: Hao Yang Sun, Ai Xin Gu, Bi Ying Huang, Tong Zhang, Jian Ping Li, An Shan Shan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Veterinary Science
Subjects:
liver injury
grape seed proanthocyanidin
Wnt3a/β-catenin signaling pathway
endoplasmic reticulum stress
microRNA
lipid metabolism
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2022.959906/full

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