GSK2656157, a PERK Inhibitor, Alleviates Pyroptosis of Macrophages Induced by Mycobacterium <i>Bacillus Calmette–Guerin</i> Infection

GSK2656157, a PERK Inhibitor, Alleviates Pyroptosis of Macrophages Induced by Mycobacterium <i>Bacillus Calmette–Guerin</i> Infection

Tuberculosis (TB) is the leading cause of human death worldwide due to <i>Mycobacterium tuberculosis</i> (Mtb) infection. Mtb infection can cause macrophage pyroptosis. PERK, as a signaling pathway protein on the endoplasmic reticulum, plays an important role in infectious diseases. It i...

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Bibliographic Details
Main Authors: Boli Ma, Xueyi Nie, Lei Liu, Mengyuan Li, Qi Chen, Yueyang Liu, Yuxin Hou, Yi Yang, Jinrui Xu
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:International Journal of Molecular Sciences
Subjects:
PERK
<i>Bacillus Calmette–Guerin</i>
macrophages
pyroptosis
Online Access:https://www.mdpi.com/1422-0067/24/22/16239

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