Control of IGFBP-2 expression by steroids and peptide hormones in vertebrates

Control of IGFBP-2 expression by steroids and peptide hormones in vertebrates

IGFBP-2 (1) has been described as a brain tumor oncogene (2) and is widely expressed in cancers from different origins (3-8). IGFBP-2 alone cannot cause malignant transformation, yet progression of brain tumors to higher grade (9) and even has been provided as a protective element in earlier stages...

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Bibliographic Details
Main Authors: Andreas eHoeflich, Elisa eWirthgen, David eRobert, Carl Friedrich eClassen, Marion eSpitschak, Julia eBrenmoehl
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-04-01
Series:Frontiers in Endocrinology
Subjects:
Estradiol
Peptide Hormones
Steroids
IGFBP-2
vetrebrates
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2014.00043/full

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