The effects of the coronavirus disease pandemic on intravenous thrombolytic therapy among patients with acute ischemic stroke in Dalian, China
Abstract Background We investigated the influence of the coronavirus disease 2019 (COVID-19) pandemic on the number of patients with acute ischemic stroke who received intravenous thrombolytic therapy (ITT) in Dalian, China, in 2020. Methods This retrospective descriptive study, conducted from Febru...
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| Format: | Article |
| Language: | English |
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BMC
2023-01-01
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| Series: | BMC Neurology |
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| Online Access: | https://doi.org/10.1186/s12883-023-03053-5 |
| _version_ | 1797952486564167680 |
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| author | Xin Pan Shubei Ma Xiaowen Sui Lili Xie Furong Li Zhengping Cheng Li Cui Hongling Zhao |
| author_facet | Xin Pan Shubei Ma Xiaowen Sui Lili Xie Furong Li Zhengping Cheng Li Cui Hongling Zhao |
| author_sort | Xin Pan |
| collection | DOAJ |
| description | Abstract Background We investigated the influence of the coronavirus disease 2019 (COVID-19) pandemic on the number of patients with acute ischemic stroke who received intravenous thrombolytic therapy (ITT) in Dalian, China, in 2020. Methods This retrospective descriptive study, conducted from February 1, 2020, to August 31, 2020, examined 13 hospitals in Dalian that participated in the “stroke emergency map”. To use this “stroke emergency map” of China, patients followed the official “Stroke Map” WeChat account and dialed 120 for emergency medical services. We analyzed the number of patients with acute ischemic stroke who underwent ITT. In particular, we examined the onset-to-door time (ODT), door-to-needle time (DNT), onset-to-needle time (ONT), mode of transportation to the hospital, and National Institutes of Health Stroke Scale (NIHSS) scores before and after ITT. Data were collected for the aforementioned period and compared with the 2021 baseline data from the same time of year. The Mann‒Whitney U test was performed for data analysis. Results Compared with the data from 2020, the number of patients with acute ischemic stroke who underwent ITT increased (from 735 to 1719 cases) in 2021, but the DNT decreased (from 59 to 45 min; P = 0.002). Moreover, 83.9% of patients in 2020 presented to the hospital without ambulance transport, compared to 81.1% of patients in the 2021 non-COVID-19 pandemic period. Patients with NIHSS scores of 6–14 were more likely to call an ambulance for transport to the hospital than to transport themselves to the emergency department. Conclusions During the 2020 COVID-19 pandemic, the DNT was prolonged as a result of strengthened fever surveillance. In 2021, the number of patients with acute ischemic stroke who underwent ITT increased compared to the previous year. Notably, the growth in the number of patients with acute ischemic stroke who underwent ITT benefited from both the “stroke emergency map” of China and the “green channel,” a novel treatment approach that focuses on the rational design of the rescue process. Trial registration. Our study was a retrospective descriptive study, not a clinical trial, thus we did not have to register for clinical trials. |
| first_indexed | 2024-04-10T22:47:06Z |
| format | Article |
| id | doaj.art-70936d005d754b41abecf64b7110fc4d |
| institution | Directory Open Access Journal |
| issn | 1471-2377 |
| language | English |
| last_indexed | 2024-04-10T22:47:06Z |
| publishDate | 2023-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Neurology |
| spelling | doaj.art-70936d005d754b41abecf64b7110fc4d2023-01-15T12:15:00ZengBMCBMC Neurology1471-23772023-01-012311510.1186/s12883-023-03053-5The effects of the coronavirus disease pandemic on intravenous thrombolytic therapy among patients with acute ischemic stroke in Dalian, ChinaXin Pan0Shubei Ma1Xiaowen Sui2Lili Xie3Furong Li4Zhengping Cheng5Li Cui6Hongling Zhao7Department of Neurology, Dalian Municipal Central Hospital Affiliated With Dalian Medical UniversityDepartment of Neurology, Dalian Municipal Central Hospital Affiliated With Dalian Medical UniversityDepartment of Neurology, Dalian Municipal Central Hospital Affiliated With Dalian Medical UniversityDepartment of Neurology, Dalian Municipal Central Hospital Affiliated With Dalian Medical UniversityDepartment of Neurology, Dalian Municipal Central Hospital Affiliated With Dalian Medical UniversityDepartment of Neurology, Dalian Municipal Central Hospital Affiliated With Dalian Medical UniversityDepartment of Neurology, Dalian Municipal Central Hospital Affiliated With Dalian Medical UniversityDepartment of Neurology, Dalian Municipal Central Hospital Affiliated With Dalian Medical UniversityAbstract Background We investigated the influence of the coronavirus disease 2019 (COVID-19) pandemic on the number of patients with acute ischemic stroke who received intravenous thrombolytic therapy (ITT) in Dalian, China, in 2020. Methods This retrospective descriptive study, conducted from February 1, 2020, to August 31, 2020, examined 13 hospitals in Dalian that participated in the “stroke emergency map”. To use this “stroke emergency map” of China, patients followed the official “Stroke Map” WeChat account and dialed 120 for emergency medical services. We analyzed the number of patients with acute ischemic stroke who underwent ITT. In particular, we examined the onset-to-door time (ODT), door-to-needle time (DNT), onset-to-needle time (ONT), mode of transportation to the hospital, and National Institutes of Health Stroke Scale (NIHSS) scores before and after ITT. Data were collected for the aforementioned period and compared with the 2021 baseline data from the same time of year. The Mann‒Whitney U test was performed for data analysis. Results Compared with the data from 2020, the number of patients with acute ischemic stroke who underwent ITT increased (from 735 to 1719 cases) in 2021, but the DNT decreased (from 59 to 45 min; P = 0.002). Moreover, 83.9% of patients in 2020 presented to the hospital without ambulance transport, compared to 81.1% of patients in the 2021 non-COVID-19 pandemic period. Patients with NIHSS scores of 6–14 were more likely to call an ambulance for transport to the hospital than to transport themselves to the emergency department. Conclusions During the 2020 COVID-19 pandemic, the DNT was prolonged as a result of strengthened fever surveillance. In 2021, the number of patients with acute ischemic stroke who underwent ITT increased compared to the previous year. Notably, the growth in the number of patients with acute ischemic stroke who underwent ITT benefited from both the “stroke emergency map” of China and the “green channel,” a novel treatment approach that focuses on the rational design of the rescue process. Trial registration. Our study was a retrospective descriptive study, not a clinical trial, thus we did not have to register for clinical trials.https://doi.org/10.1186/s12883-023-03053-5Acute ischemic strokeCOVID-19Intravenous thrombolytic therapyStroke emergency mapsGreen channel |
| spellingShingle | Xin Pan Shubei Ma Xiaowen Sui Lili Xie Furong Li Zhengping Cheng Li Cui Hongling Zhao The effects of the coronavirus disease pandemic on intravenous thrombolytic therapy among patients with acute ischemic stroke in Dalian, China BMC Neurology Acute ischemic stroke COVID-19 Intravenous thrombolytic therapy Stroke emergency maps Green channel |
| title | The effects of the coronavirus disease pandemic on intravenous thrombolytic therapy among patients with acute ischemic stroke in Dalian, China |
| title_full | The effects of the coronavirus disease pandemic on intravenous thrombolytic therapy among patients with acute ischemic stroke in Dalian, China |
| title_fullStr | The effects of the coronavirus disease pandemic on intravenous thrombolytic therapy among patients with acute ischemic stroke in Dalian, China |
| title_full_unstemmed | The effects of the coronavirus disease pandemic on intravenous thrombolytic therapy among patients with acute ischemic stroke in Dalian, China |
| title_short | The effects of the coronavirus disease pandemic on intravenous thrombolytic therapy among patients with acute ischemic stroke in Dalian, China |
| title_sort | effects of the coronavirus disease pandemic on intravenous thrombolytic therapy among patients with acute ischemic stroke in dalian china |
| topic | Acute ischemic stroke COVID-19 Intravenous thrombolytic therapy Stroke emergency maps Green channel |
| url | https://doi.org/10.1186/s12883-023-03053-5 |
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