Cefuroxime-associated Kounis syndrome with unique peculiarity in perioperative prophylaxis
Cefuroxime is a broad spectrum antibacterial agent administered in cases of perioperative prophylaxis. Kounis syndrome is defined as the concurrence of anaphylactic events with acute coronary syndromes. Limited data is available for cefuroxime-associated Kounis syndrome in perioperative prophylaxis....
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2018-11-01
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| Series: | Journal of Infection and Public Health |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1876034118300340 |
| _version_ | 1819078073264373760 |
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| author | Jie Gao Yuan Gao Jingjing Ma |
| author_facet | Jie Gao Yuan Gao Jingjing Ma |
| author_sort | Jie Gao |
| collection | DOAJ |
| description | Cefuroxime is a broad spectrum antibacterial agent administered in cases of perioperative prophylaxis. Kounis syndrome is defined as the concurrence of anaphylactic events with acute coronary syndromes. Limited data is available for cefuroxime-associated Kounis syndrome in perioperative prophylaxis. We report the case of a 37-year-old woman undergoing bilateral sweat gland resection who presented with Kounis syndrome following cefuroxime infusion for perioperative prophylaxis. The patient had severe symptoms and unique manifestations that never been reported before: pink frothy sputum indicating heart failure, due to severe systolic dysfunction requiring invasive ventilation and intra-aortic balloon counter-pulsation. Cefuroxime-associated Kounis syndrome has several unique and life-threatening peculiarities which broaden our understanding of clinical and laboratory characteristics. It is important for physicians to be aware of possible cardiovascular complications in perioperative cefuroxime prophylaxis. Keywords: Cefuroxime, Kounis syndrome, Perioperative prophylaxis |
| first_indexed | 2024-12-21T19:07:17Z |
| format | Article |
| id | doaj.art-70989932c0e249aea71d461bc5aff593 |
| institution | Directory Open Access Journal |
| issn | 1876-0341 |
| language | English |
| last_indexed | 2024-12-21T19:07:17Z |
| publishDate | 2018-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Infection and Public Health |
| spelling | doaj.art-70989932c0e249aea71d461bc5aff5932022-12-21T18:53:17ZengElsevierJournal of Infection and Public Health1876-03412018-11-01116889892Cefuroxime-associated Kounis syndrome with unique peculiarity in perioperative prophylaxisJie Gao0Yuan Gao1Jingjing Ma2The First Affiliated Hospital, Department of Pharmacy, School of Medicine, Soochow University, Suzhou, ChinaThe First Affiliated Hospital, Department of Pharmacy, School of Medicine, Soochow University, Suzhou, ChinaCorresponding author at: The First Affiliated Hospital, Department of Pharmacy, School of Medicine, Soochow University, 188 Shizi Rd, Suzhou 215006, China.; The First Affiliated Hospital, Department of Pharmacy, School of Medicine, Soochow University, Suzhou, ChinaCefuroxime is a broad spectrum antibacterial agent administered in cases of perioperative prophylaxis. Kounis syndrome is defined as the concurrence of anaphylactic events with acute coronary syndromes. Limited data is available for cefuroxime-associated Kounis syndrome in perioperative prophylaxis. We report the case of a 37-year-old woman undergoing bilateral sweat gland resection who presented with Kounis syndrome following cefuroxime infusion for perioperative prophylaxis. The patient had severe symptoms and unique manifestations that never been reported before: pink frothy sputum indicating heart failure, due to severe systolic dysfunction requiring invasive ventilation and intra-aortic balloon counter-pulsation. Cefuroxime-associated Kounis syndrome has several unique and life-threatening peculiarities which broaden our understanding of clinical and laboratory characteristics. It is important for physicians to be aware of possible cardiovascular complications in perioperative cefuroxime prophylaxis. Keywords: Cefuroxime, Kounis syndrome, Perioperative prophylaxishttp://www.sciencedirect.com/science/article/pii/S1876034118300340 |
| spellingShingle | Jie Gao Yuan Gao Jingjing Ma Cefuroxime-associated Kounis syndrome with unique peculiarity in perioperative prophylaxis Journal of Infection and Public Health |
| title | Cefuroxime-associated Kounis syndrome with unique peculiarity in perioperative prophylaxis |
| title_full | Cefuroxime-associated Kounis syndrome with unique peculiarity in perioperative prophylaxis |
| title_fullStr | Cefuroxime-associated Kounis syndrome with unique peculiarity in perioperative prophylaxis |
| title_full_unstemmed | Cefuroxime-associated Kounis syndrome with unique peculiarity in perioperative prophylaxis |
| title_short | Cefuroxime-associated Kounis syndrome with unique peculiarity in perioperative prophylaxis |
| title_sort | cefuroxime associated kounis syndrome with unique peculiarity in perioperative prophylaxis |
| url | http://www.sciencedirect.com/science/article/pii/S1876034118300340 |
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