Endometriosis, Oocyte, and Embryo Quality
Endometriosis is a common finding among women with infertility, and women who are diagnosed with endometriosis are almost twice as likely to experience infertility. Mechanisms by which endometriosis causes infertility remain poorly understood. In this review, we evaluate the current literature on th...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-06-01
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| Series: | Journal of Clinical Medicine |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2077-0383/12/13/4186 |
| _version_ | 1797591487269044224 |
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| author | Sania Latif Ertan Saridogan |
| author_facet | Sania Latif Ertan Saridogan |
| author_sort | Sania Latif |
| collection | DOAJ |
| description | Endometriosis is a common finding among women with infertility, and women who are diagnosed with endometriosis are almost twice as likely to experience infertility. Mechanisms by which endometriosis causes infertility remain poorly understood. In this review, we evaluate the current literature on the impact of endometriosis on oocyte and embryo quality. The presence of endometriosis evidently reduces ovarian reserve, oocyte quality, and embryo quality; however, this does not appear to translate to a clear clinical impact. Analysis of data from large assisted reproduction technology registries has shown that women with endometriosis have a lower oocyte yield but no reduction in reproductive outcomes. There is a need for future studies in the form of well-designed randomized controlled trials to further evaluate the role of surgical and medical treatment options in women with endometriosis undergoing assisted conception. |
| first_indexed | 2024-03-11T01:38:06Z |
| format | Article |
| id | doaj.art-709d1f57d42a43cda402be784e15aa51 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-11T01:38:06Z |
| publishDate | 2023-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-709d1f57d42a43cda402be784e15aa512023-11-18T16:50:15ZengMDPI AGJournal of Clinical Medicine2077-03832023-06-011213418610.3390/jcm12134186Endometriosis, Oocyte, and Embryo QualitySania Latif0Ertan Saridogan1Reproductive Medicine Unit, University College London Hospital, London NW1 2BU, UKReproductive Medicine Unit, University College London Hospital, London NW1 2BU, UKEndometriosis is a common finding among women with infertility, and women who are diagnosed with endometriosis are almost twice as likely to experience infertility. Mechanisms by which endometriosis causes infertility remain poorly understood. In this review, we evaluate the current literature on the impact of endometriosis on oocyte and embryo quality. The presence of endometriosis evidently reduces ovarian reserve, oocyte quality, and embryo quality; however, this does not appear to translate to a clear clinical impact. Analysis of data from large assisted reproduction technology registries has shown that women with endometriosis have a lower oocyte yield but no reduction in reproductive outcomes. There is a need for future studies in the form of well-designed randomized controlled trials to further evaluate the role of surgical and medical treatment options in women with endometriosis undergoing assisted conception.https://www.mdpi.com/2077-0383/12/13/4186endometriosisin vitro fertilizationoocytesembryonic structures |
| spellingShingle | Sania Latif Ertan Saridogan Endometriosis, Oocyte, and Embryo Quality Journal of Clinical Medicine endometriosis in vitro fertilization oocytes embryonic structures |
| title | Endometriosis, Oocyte, and Embryo Quality |
| title_full | Endometriosis, Oocyte, and Embryo Quality |
| title_fullStr | Endometriosis, Oocyte, and Embryo Quality |
| title_full_unstemmed | Endometriosis, Oocyte, and Embryo Quality |
| title_short | Endometriosis, Oocyte, and Embryo Quality |
| title_sort | endometriosis oocyte and embryo quality |
| topic | endometriosis in vitro fertilization oocytes embryonic structures |
| url | https://www.mdpi.com/2077-0383/12/13/4186 |
| work_keys_str_mv | AT sanialatif endometriosisoocyteandembryoquality AT ertansaridogan endometriosisoocyteandembryoquality |