A New Triterpenoid Saponin from Abrus precatorius Linn
A new triterpenoid saponin, 3-O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl subprogenin D (1), together with six known triterpenoids: subprogenin D (2), abrusgenic acid (3), triptotriterpenic acid B (4), abruslactone A (5), abrusogenin (6) and abrusoside C (7) were isolated from the leaves and stems...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2011-12-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1420-3049/17/1/295/ |
| _version_ | 1811253745145610240 |
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| author | Si Zhang Cai-Guo Huang Chuan-Rong Li Zhi-Hui Xiao Fa-Zuo Wang Ai-Jun Sun |
| author_facet | Si Zhang Cai-Guo Huang Chuan-Rong Li Zhi-Hui Xiao Fa-Zuo Wang Ai-Jun Sun |
| author_sort | Si Zhang |
| collection | DOAJ |
| description | A new triterpenoid saponin, 3-O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl subprogenin D (1), together with six known triterpenoids: subprogenin D (2), abrusgenic acid (3), triptotriterpenic acid B (4), abruslactone A (5), abrusogenin (6) and abrusoside C (7) were isolated from the leaves and stems of Abrus precatorius. Their structures were elucidated on the basis of physical and NMR analysis, respectively. Compounds 5 and 6 showed moderate cytotoxicity against MCF-7, SW1990, Hela, and Du-145 cell lines. Compounds 1, 2 and 4 were isolated from this plant for the first time. |
| first_indexed | 2024-04-12T16:55:46Z |
| format | Article |
| id | doaj.art-70a311461fe246c0aa24047d50c40af9 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-04-12T16:55:46Z |
| publishDate | 2011-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-70a311461fe246c0aa24047d50c40af92022-12-22T03:24:14ZengMDPI AGMolecules1420-30492011-12-0117129530210.3390/molecules17010295A New Triterpenoid Saponin from Abrus precatorius LinnSi ZhangCai-Guo HuangChuan-Rong LiZhi-Hui XiaoFa-Zuo WangAi-Jun SunA new triterpenoid saponin, 3-O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl subprogenin D (1), together with six known triterpenoids: subprogenin D (2), abrusgenic acid (3), triptotriterpenic acid B (4), abruslactone A (5), abrusogenin (6) and abrusoside C (7) were isolated from the leaves and stems of Abrus precatorius. Their structures were elucidated on the basis of physical and NMR analysis, respectively. Compounds 5 and 6 showed moderate cytotoxicity against MCF-7, SW1990, Hela, and Du-145 cell lines. Compounds 1, 2 and 4 were isolated from this plant for the first time.http://www.mdpi.com/1420-3049/17/1/295/Abrus precarorius Linntriterpenoidsaponincytotoxicity |
| spellingShingle | Si Zhang Cai-Guo Huang Chuan-Rong Li Zhi-Hui Xiao Fa-Zuo Wang Ai-Jun Sun A New Triterpenoid Saponin from Abrus precatorius Linn Molecules Abrus precarorius Linn triterpenoid saponin cytotoxicity |
| title | A New Triterpenoid Saponin from Abrus precatorius Linn |
| title_full | A New Triterpenoid Saponin from Abrus precatorius Linn |
| title_fullStr | A New Triterpenoid Saponin from Abrus precatorius Linn |
| title_full_unstemmed | A New Triterpenoid Saponin from Abrus precatorius Linn |
| title_short | A New Triterpenoid Saponin from Abrus precatorius Linn |
| title_sort | new triterpenoid saponin from abrus precatorius linn |
| topic | Abrus precarorius Linn triterpenoid saponin cytotoxicity |
| url | http://www.mdpi.com/1420-3049/17/1/295/ |
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