Polyamine Biosynthetic Pathway as a Drug Target for Osteosarcoma Therapy

Polyamine Biosynthetic Pathway as a Drug Target for Osteosarcoma Therapy

Osteosarcoma (OS) is the most common bone tumor in children. Polyamines (PAs) are ubiquitous cations involved in many cell processes including tumor development, invasion and metastasis. In other pediatric cancer models, inhibition of the PA biosynthesis pathway with ornithine decarboxylase (ODC) in...

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Xehetasun bibliografikoak
Egile Nagusiak: Rebecca R. Weicht, Chad R. Schultz, Dirk Geerts, Katie L. Uhl, André S. Bachmann
Formatua: Artikulua
Hizkuntza:English
Argitaratua: MDPI AG 2018-08-01
Saila:Medical Sciences
Gaiak:
cell differentiation
DFMO
ornithine decarboxylase
osteosarcoma
polyamines
Sarrera elektronikoa:http://www.mdpi.com/2076-3271/6/3/65

Internet

http://www.mdpi.com/2076-3271/6/3/65

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