Polyamine Biosynthetic Pathway as a Drug Target for Osteosarcoma Therapy
Osteosarcoma (OS) is the most common bone tumor in children. Polyamines (PAs) are ubiquitous cations involved in many cell processes including tumor development, invasion and metastasis. In other pediatric cancer models, inhibition of the PA biosynthesis pathway with ornithine decarboxylase (ODC) in...
| Auteurs principaux: | , , , , |
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| Format: | Article |
| Langue: | English |
| Publié: |
MDPI AG
2018-08-01
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| Collection: | Medical Sciences |
| Sujets: | |
| Accès en ligne: | http://www.mdpi.com/2076-3271/6/3/65 |