Polyamine Biosynthetic Pathway as a Drug Target for Osteosarcoma Therapy
Osteosarcoma (OS) is the most common bone tumor in children. Polyamines (PAs) are ubiquitous cations involved in many cell processes including tumor development, invasion and metastasis. In other pediatric cancer models, inhibition of the PA biosynthesis pathway with ornithine decarboxylase (ODC) in...
| Главные авторы: | , , , , |
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| Формат: | Статья |
| Язык: | English |
| Опубликовано: |
MDPI AG
2018-08-01
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| Серии: | Medical Sciences |
| Предметы: | |
| Online-ссылка: | http://www.mdpi.com/2076-3271/6/3/65 |