Polyamine Biosynthetic Pathway as a Drug Target for Osteosarcoma Therapy

Polyamine Biosynthetic Pathway as a Drug Target for Osteosarcoma Therapy

Osteosarcoma (OS) is the most common bone tumor in children. Polyamines (PAs) are ubiquitous cations involved in many cell processes including tumor development, invasion and metastasis. In other pediatric cancer models, inhibition of the PA biosynthesis pathway with ornithine decarboxylase (ODC) in...

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Chi tiết về thư mục
Những tác giả chính: Rebecca R. Weicht, Chad R. Schultz, Dirk Geerts, Katie L. Uhl, André S. Bachmann
Định dạng: Bài viết
Ngôn ngữ:English
Được phát hành: MDPI AG 2018-08-01
Loạt:Medical Sciences
Những chủ đề:
cell differentiation
DFMO
ornithine decarboxylase
osteosarcoma
polyamines
Truy cập trực tuyến:http://www.mdpi.com/2076-3271/6/3/65

Internet

http://www.mdpi.com/2076-3271/6/3/65

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