New Mediators and Growth Factors Affecting Pterium Growth
Pterjium is an ocular surface disorder and is a pathologic result of corneal invasion of the fibro-vascular proliferation of the bulb conjunctiva in the region corresponding to the lid space. Pterjium is a disease with high rates of recurrence after surgery. Nowadays, along with several new techniqu...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Alanya Alaaddin Keykubat University
2017-07-01
|
| Series: | Acta Medica Alanya |
| Subjects: | |
| Online Access: | https://dergipark.org.tr/en/pub/medalanya/issue/30435/294045?publisher=alku |
| _version_ | 1797911121496113152 |
|---|---|
| author | Leyla Eryi̇ği̇t Eroğul |
| author_facet | Leyla Eryi̇ği̇t Eroğul |
| author_sort | Leyla Eryi̇ği̇t Eroğul |
| collection | DOAJ |
| description | Pterjium is an ocular surface disorder and is a pathologic result of
corneal invasion of the fibro-vascular proliferation of the bulb conjunctiva in
the region corresponding to the lid space. Pterjium is a disease with high
rates of recurrence after surgery. Nowadays, along with several new techniques
that are used to prevent recurrence, antineoplastics are also used to stop the
growth. Various growth factors and mediators, like some neoplasms, have been
found to be effective in pterygium growth, invasion and relapse. In addition to
growth factors such as stem cell factor and VEGF, an increase in histamine,
carbonic anhydrase activity, in number of eph B4, and in nestin release was
found while a decrease in IGFBP3 release was found. Studies are currently
underway to stop the growth of pterygium and prevent recurrence. |
| first_indexed | 2024-04-10T11:35:25Z |
| format | Article |
| id | doaj.art-70a435cd7e114c6db74680aeac4da899 |
| institution | Directory Open Access Journal |
| issn | 2587-0319 |
| language | English |
| last_indexed | 2024-04-10T11:35:25Z |
| publishDate | 2017-07-01 |
| publisher | Alanya Alaaddin Keykubat University |
| record_format | Article |
| series | Acta Medica Alanya |
| spelling | doaj.art-70a435cd7e114c6db74680aeac4da8992023-02-15T16:17:51ZengAlanya Alaaddin Keykubat UniversityActa Medica Alanya2587-03192017-07-01129910210.30565/medalanya.294045727New Mediators and Growth Factors Affecting Pterium GrowthLeyla Eryi̇ği̇t Eroğul0Afyonkarahisar Devlet Hastanesi, Göz Hastalıkları Kliniği, Afyonkarahisar, TürkiyePterjium is an ocular surface disorder and is a pathologic result of corneal invasion of the fibro-vascular proliferation of the bulb conjunctiva in the region corresponding to the lid space. Pterjium is a disease with high rates of recurrence after surgery. Nowadays, along with several new techniques that are used to prevent recurrence, antineoplastics are also used to stop the growth. Various growth factors and mediators, like some neoplasms, have been found to be effective in pterygium growth, invasion and relapse. In addition to growth factors such as stem cell factor and VEGF, an increase in histamine, carbonic anhydrase activity, in number of eph B4, and in nestin release was found while a decrease in IGFBP3 release was found. Studies are currently underway to stop the growth of pterygium and prevent recurrence.https://dergipark.org.tr/en/pub/medalanya/issue/30435/294045?publisher=alkupterjiumvegfhistaminkarbonik anhidrazigfbp3ephinephb4nestinpterjiumvegfhistaminecarbonic anhydraseigfbp3ephinephb4nestin |
| spellingShingle | Leyla Eryi̇ği̇t Eroğul New Mediators and Growth Factors Affecting Pterium Growth Acta Medica Alanya pterjium vegf histamin karbonik anhidraz igfbp3 ephin ephb4 nestin pterjium vegf histamine carbonic anhydrase igfbp3 ephin ephb4 nestin |
| title | New Mediators and Growth Factors Affecting Pterium Growth |
| title_full | New Mediators and Growth Factors Affecting Pterium Growth |
| title_fullStr | New Mediators and Growth Factors Affecting Pterium Growth |
| title_full_unstemmed | New Mediators and Growth Factors Affecting Pterium Growth |
| title_short | New Mediators and Growth Factors Affecting Pterium Growth |
| title_sort | new mediators and growth factors affecting pterium growth |
| topic | pterjium vegf histamin karbonik anhidraz igfbp3 ephin ephb4 nestin pterjium vegf histamine carbonic anhydrase igfbp3 ephin ephb4 nestin |
| url | https://dergipark.org.tr/en/pub/medalanya/issue/30435/294045?publisher=alku |
| work_keys_str_mv | AT leylaeryigiterogul newmediatorsandgrowthfactorsaffectingpteriumgrowth |