Heparanase regulates EMT and cancer stem cell properties in prostate tumors

Heparanase regulates EMT and cancer stem cell properties in prostate tumors

Prostate cancer displays a certain phenotypic plasticity that allows for the transition of cells from the epithelial to the mesenchymal state. This process, known as epithelial–mesenchymal transition (EMT), is one of the factors that give the tumor cells greater invasive and migratory capacity with...

Full description

Bibliographic Details
Main Authors: Valentina Masola, Marco Franchi, Gianluigi Zaza, Francesca Mansa Atsina, Giovanni Gambaro, Maurizio Onisto
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Oncology
Subjects:
prostate cancer
heparanase
epithelial to mesenchymal transition
cancer stem cells
in vitro
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.918419/full

Similar Items

Similar Items