Emerging roles of tRNA-derived small RNAs in cancer biology

Abstract Transfer RNAs (tRNAs) play an essential role in mRNA translation by delivering amino acids to growing polypeptide chains. Recent data demonstrate that tRNAs can be cleaved by ribonucleases, and the resultant cleavage products, tRNA-derived small RNAs (tsRNAs), have crucial roles in physiolo...

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Bibliographic Details
Main Authors: Saebyeol Lee, Jungeun Kim, Paul N. Valdmanis, Hak Kyun Kim
Format: Article
Language:English
Published: Nature Publishing Group 2023-07-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-023-01038-5