Image-guided focal therapy for prostate cancer

The adoption of routine prostate specific antigen screening has led to the discovery of many small and low-grade prostate cancers which have a low probability of causing mortality. These cancers, however, are often treated with radical therapies resulting in long-term side effects. There has been in...

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Bibliographic Details
Main Authors: Sandeep Sankineni, Bradford J. Wood, Soroush Rais-Bahrami, Annerleim Walton Diaz, Anthony N. Hoang, Peter A Pinto, Peter L. Choyke, Barış Türkbey
Format: Article
Language:English
Published: Galenos Publishing House 2014-11-01
Series:Diagnostic and Interventional Radiology
Online Access: http://www.dirjournal.org/archives/archive-detail/article-preview/mage-guided-focal-therapy-for-prostate-cancer/56006
Description
Summary:The adoption of routine prostate specific antigen screening has led to the discovery of many small and low-grade prostate cancers which have a low probability of causing mortality. These cancers, however, are often treated with radical therapies resulting in long-term side effects. There has been increasing interest in minimally invasive focal therapies to treat these tumors. While imaging modalities have improved rapidly over the past decade, similar advances in image-guided therapy are now starting to emerge—potentially achieving equivalent oncologic efficacy while avoiding the side effects of conventional radical surgery. The purpose of this article is to review the existing literature regarding the basis of various focal therapy techniques such as cryotherapy, microwave, laser, and high intensity focused ul­trasound, and to discuss the results of recent clinical trials that demonstrate early outcomes in patients with prostate cancer.
ISSN:1305-3825
1305-3612