Case report: Malignant teratoma of the uterine corpus

<p>Abstract</p> <p>Background</p> <p>Teratomas are the commonest germ cell tumours and are most frequently found in the testes and ovary. Extragonadal teratomas are rare and mainly occur in midline structures. Uterine teratomas are extremely rare with only a few previou...

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Main Authors: Christmas Timothy, Butler-Manuel Simon, Papanikolaou Kyriakos, Lindsay Iain, Ameen Mohammed, Gray Rebecca, Poulter Daniel, Newsom-Davis Thomas, Townsend Peter, Seckl Michael
Format: Article
Language:English
Published: BMC 2009-06-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/9/195
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author Christmas Timothy
Butler-Manuel Simon
Papanikolaou Kyriakos
Lindsay Iain
Ameen Mohammed
Gray Rebecca
Poulter Daniel
Newsom-Davis Thomas
Townsend Peter
Seckl Michael
author_facet Christmas Timothy
Butler-Manuel Simon
Papanikolaou Kyriakos
Lindsay Iain
Ameen Mohammed
Gray Rebecca
Poulter Daniel
Newsom-Davis Thomas
Townsend Peter
Seckl Michael
author_sort Christmas Timothy
collection DOAJ
description <p>Abstract</p> <p>Background</p> <p>Teratomas are the commonest germ cell tumours and are most frequently found in the testes and ovary. Extragonadal teratomas are rare and mainly occur in midline structures. Uterine teratomas are extremely rare with only a few previous case reports, usually involving mature teratomas of the uterine cervix.</p> <p>Case Presentation</p> <p>We report an 82-year-old lady presenting with post-menopausal bleeding. Initial investigations revealed a benign teratoma of the uterus which was removed. Her symptoms persisted and a recurrent, now malignant, teratoma of the uterine corpus was resected at hysterectomy. Six months after surgery she relapsed with para-aortic lymphadenopathy and was treated with a taxane, etoposide and cisplatin-containing chemotherapy regimen followed by retroperitoneal lymph node dissection.</p> <p>Conclusion</p> <p>In this report we discuss the aetiology, diagnosis and management of uterine teratomas, and review previous case studies.</p>
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spelling doaj.art-70a7c24d06684b3d86e149b5a951465d2022-12-22T03:26:13ZengBMCBMC Cancer1471-24072009-06-019119510.1186/1471-2407-9-195Case report: Malignant teratoma of the uterine corpusChristmas TimothyButler-Manuel SimonPapanikolaou KyriakosLindsay IainAmeen MohammedGray RebeccaPoulter DanielNewsom-Davis ThomasTownsend PeterSeckl Michael<p>Abstract</p> <p>Background</p> <p>Teratomas are the commonest germ cell tumours and are most frequently found in the testes and ovary. Extragonadal teratomas are rare and mainly occur in midline structures. Uterine teratomas are extremely rare with only a few previous case reports, usually involving mature teratomas of the uterine cervix.</p> <p>Case Presentation</p> <p>We report an 82-year-old lady presenting with post-menopausal bleeding. Initial investigations revealed a benign teratoma of the uterus which was removed. Her symptoms persisted and a recurrent, now malignant, teratoma of the uterine corpus was resected at hysterectomy. Six months after surgery she relapsed with para-aortic lymphadenopathy and was treated with a taxane, etoposide and cisplatin-containing chemotherapy regimen followed by retroperitoneal lymph node dissection.</p> <p>Conclusion</p> <p>In this report we discuss the aetiology, diagnosis and management of uterine teratomas, and review previous case studies.</p>http://www.biomedcentral.com/1471-2407/9/195
spellingShingle Christmas Timothy
Butler-Manuel Simon
Papanikolaou Kyriakos
Lindsay Iain
Ameen Mohammed
Gray Rebecca
Poulter Daniel
Newsom-Davis Thomas
Townsend Peter
Seckl Michael
Case report: Malignant teratoma of the uterine corpus
BMC Cancer
title Case report: Malignant teratoma of the uterine corpus
title_full Case report: Malignant teratoma of the uterine corpus
title_fullStr Case report: Malignant teratoma of the uterine corpus
title_full_unstemmed Case report: Malignant teratoma of the uterine corpus
title_short Case report: Malignant teratoma of the uterine corpus
title_sort case report malignant teratoma of the uterine corpus
url http://www.biomedcentral.com/1471-2407/9/195
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