A promising nucleic acid therapy drug: DNAzymes and its delivery system

A promising nucleic acid therapy drug: DNAzymes and its delivery system

Based on the development of nucleic acid therapeutic drugs, DNAzymes obtained through in vitro selection technology in 1994 are gradually being sought. DNAzymes are single-stranded DNA molecules with catalytic function, which specifically cleave RNA under the action of metal ions. Various in vivo an...

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Bibliographic Details
Main Authors: Lang Xiao, Yan Zhao, Meng Yang, Guangxin Luan, Ting Du, Shanshan Deng, Xu Jia
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Molecular Biosciences
Subjects:
DNAzymes
in vitro selection
catalytic function
RNA cleavage
therapeutic agent
gene expression
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2023.1270101/full

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