Identification of highly reliable risk genes for Alzheimer’s disease through joint-tissue integrative analysis

Identification of highly reliable risk genes for Alzheimer’s disease through joint-tissue integrative analysis

Numerous genetic variants associated with Alzheimer’s disease (AD) have been identified through genome-wide association studies (GWAS), but their interpretation is hindered by the strong linkage disequilibrium (LD) among the variants, making it difficult to identify the causal variants directly. To...

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Bibliographic Details
Main Authors:	Yong Heng Wang, Pan Pan Luo, Ao Yi Geng, Xinwei Li, Tai-Hang Liu, Yi Jie He, Lin Huang, Ya Qin Tang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-06-01
Series:	Frontiers in Aging Neuroscience
Subjects:	GWAS TWAS Mendelian Randomization eQTL Alzheimer’s disease
Online Access:	https://www.frontiersin.org/articles/10.3389/fnagi.2023.1183119/full

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