Lack of Correlation between Plasma Neuropeptide Y and Typical and Atypical Febrile Seizures

It is known that neuropeptide Y which is widely distributed throughout the central nervous system is able to prevent seizures in animals. There are limited studies about the role of neuropeptide Y in febrile seizures. This study was conducted to evaluate the association between plasma neuropeptide Y...

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Main Authors: Hamid Reza Sarokhani, Mohsen Nazari, Parviz Ayazi, Abolfazl Mahyar, Mohammad Mahdi Daneshi-Kohan, Amir Javadi
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2013-04-01
Series:Acta Medica Iranica
Subjects:
Online Access:http://acta.tums.ac.ir/index.php/acta/article/view/4684/4306
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author Hamid Reza Sarokhani
Mohsen Nazari
Parviz Ayazi
Abolfazl Mahyar
Mohammad Mahdi Daneshi-Kohan
Amir Javadi
author_facet Hamid Reza Sarokhani
Mohsen Nazari
Parviz Ayazi
Abolfazl Mahyar
Mohammad Mahdi Daneshi-Kohan
Amir Javadi
author_sort Hamid Reza Sarokhani
collection DOAJ
description It is known that neuropeptide Y which is widely distributed throughout the central nervous system is able to prevent seizures in animals. There are limited studies about the role of neuropeptide Y in febrile seizures. This study was conducted to evaluate the association between plasma neuropeptide Y level and febrile seizures in children. Seventy six patients with typical and atypical febrile seizures (each group 38 patients) and 38 sex and age matched control subjects were enrolled. The mean plasma levels of neuropeptide Y in typical and atypical febrile seizures were 90.60±28.01 and 97.34±41.27 pmol/l respectively. This value in control group was 88.94±32.66 pmol/l. There was no significant differences between groups regarding plasma neuropeptide Y level (P=0.532). Also, there was no significant difference in comparison with case groups (P=0.40). This study revealed that there is no association between plasma neuropeptide Y and febrile seizures.
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spelling doaj.art-70b0e8b8bac0478c944f2890c8e4943c2022-12-22T00:04:24ZengTehran University of Medical SciencesActa Medica Iranica0044-60251735-96942013-04-01514246249Lack of Correlation between Plasma Neuropeptide Y and Typical and Atypical Febrile SeizuresHamid Reza SarokhaniMohsen NazariParviz AyaziAbolfazl MahyarMohammad Mahdi Daneshi-KohanAmir JavadiIt is known that neuropeptide Y which is widely distributed throughout the central nervous system is able to prevent seizures in animals. There are limited studies about the role of neuropeptide Y in febrile seizures. This study was conducted to evaluate the association between plasma neuropeptide Y level and febrile seizures in children. Seventy six patients with typical and atypical febrile seizures (each group 38 patients) and 38 sex and age matched control subjects were enrolled. The mean plasma levels of neuropeptide Y in typical and atypical febrile seizures were 90.60±28.01 and 97.34±41.27 pmol/l respectively. This value in control group was 88.94±32.66 pmol/l. There was no significant differences between groups regarding plasma neuropeptide Y level (P=0.532). Also, there was no significant difference in comparison with case groups (P=0.40). This study revealed that there is no association between plasma neuropeptide Y and febrile seizures.http://acta.tums.ac.ir/index.php/acta/article/view/4684/4306Febrile SeizuresNeuropeptide Y
spellingShingle Hamid Reza Sarokhani
Mohsen Nazari
Parviz Ayazi
Abolfazl Mahyar
Mohammad Mahdi Daneshi-Kohan
Amir Javadi
Lack of Correlation between Plasma Neuropeptide Y and Typical and Atypical Febrile Seizures
Acta Medica Iranica
Febrile Seizures
Neuropeptide Y
title Lack of Correlation between Plasma Neuropeptide Y and Typical and Atypical Febrile Seizures
title_full Lack of Correlation between Plasma Neuropeptide Y and Typical and Atypical Febrile Seizures
title_fullStr Lack of Correlation between Plasma Neuropeptide Y and Typical and Atypical Febrile Seizures
title_full_unstemmed Lack of Correlation between Plasma Neuropeptide Y and Typical and Atypical Febrile Seizures
title_short Lack of Correlation between Plasma Neuropeptide Y and Typical and Atypical Febrile Seizures
title_sort lack of correlation between plasma neuropeptide y and typical and atypical febrile seizures
topic Febrile Seizures
Neuropeptide Y
url http://acta.tums.ac.ir/index.php/acta/article/view/4684/4306
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AT parvizayazi lackofcorrelationbetweenplasmaneuropeptideyandtypicalandatypicalfebrileseizures
AT abolfazlmahyar lackofcorrelationbetweenplasmaneuropeptideyandtypicalandatypicalfebrileseizures
AT mohammadmahdidaneshikohan lackofcorrelationbetweenplasmaneuropeptideyandtypicalandatypicalfebrileseizures
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