Coronary artery lesions in children with Kawasaki disease: status quo and nursing care
AimCoronary artery lesion (CAL) is a common yet serious complication in children with Kawasaki disease. The aim of the present study was to evaluate the influencing factors of CAL in children with Kawasaki disease, to provide reference for the clinical treatment and care of children with Kawasaki di...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2024-04-01
|
| Series: | Frontiers in Cardiovascular Medicine |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fcvm.2024.1272475/full |
| _version_ | 1797198718558011392 |
|---|---|
| author | Cen Chen Qiuhui Chen Tong Zhang Yanping Ling |
| author_facet | Cen Chen Qiuhui Chen Tong Zhang Yanping Ling |
| author_sort | Cen Chen |
| collection | DOAJ |
| description | AimCoronary artery lesion (CAL) is a common yet serious complication in children with Kawasaki disease. The aim of the present study was to evaluate the influencing factors of CAL in children with Kawasaki disease, to provide reference for the clinical treatment and care of children with Kawasaki disease.DesignA retrospective cohort study.MethodsChildren with Kawasaki disease treated in a tertiary hospital in China between 1 January 2021 and 31 December 2022 were selected. The characteristics and clinical data of children with Kawasaki disease were analyzed. Spearman’s correlation analysis was conducted to evaluate the relationship between CAL and the characteristics of children with Kawasaki disease. A logistic regression analysis was used to analyze the influencing factors of CAL in children with Kawasaki disease.ResultsIn total, 185 children with Kawasaki disease were included; the incidence of CAL in children with Kawasaki disease was 18.38%. Pearson’s correlation analysis showed that gender (r = 0.504), age (r = 0.611), duration of fever ≥10 days (r = 0.579), hemoglobin (Hb) (r = 0.623), and C-reactive protein (CRP) (r = 0.558) were all correlated with the CAL in children with Kawasaki disease (all p < 0.05). Logistic regression analyses showed that male [odds ratio (OR) = 2.543, 95% confidence interval (CI): 1.801–3.077, p = 0.040], age ≤2 years (OR = 3.002, 95% CI: 2.744–3.641, p = 0.012), duration of fever ≥10 days (OR = 2.089, 95% CI: 1.624–2.515, p = 0.028), Hb ≤105 g/L (OR = 1.914, 95% CI: 1.431–2.406, p = 0.013), and CRP ≥100 mg/L (OR = 2.168, 95% CI: 1.893–2.531, p = 0.035) were the risk factors of CAL in children with Kawasaki disease (all p < 0.05).ConclusionsThe incidence of CAL in children with Kawasaki disease is high and there are many related risk factors. Clinical medical workers should take early warning and carry out interventions and nursing care according to these risk factors to improve the prognosis of children with Kawasaki disease. |
| first_indexed | 2024-04-24T07:04:19Z |
| format | Article |
| id | doaj.art-70b517ee0d294f7abf6fd7471786e876 |
| institution | Directory Open Access Journal |
| issn | 2297-055X |
| language | English |
| last_indexed | 2024-04-24T07:04:19Z |
| publishDate | 2024-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cardiovascular Medicine |
| spelling | doaj.art-70b517ee0d294f7abf6fd7471786e8762024-04-22T04:37:26ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2024-04-011110.3389/fcvm.2024.12724751272475Coronary artery lesions in children with Kawasaki disease: status quo and nursing careCen ChenQiuhui ChenTong ZhangYanping LingAimCoronary artery lesion (CAL) is a common yet serious complication in children with Kawasaki disease. The aim of the present study was to evaluate the influencing factors of CAL in children with Kawasaki disease, to provide reference for the clinical treatment and care of children with Kawasaki disease.DesignA retrospective cohort study.MethodsChildren with Kawasaki disease treated in a tertiary hospital in China between 1 January 2021 and 31 December 2022 were selected. The characteristics and clinical data of children with Kawasaki disease were analyzed. Spearman’s correlation analysis was conducted to evaluate the relationship between CAL and the characteristics of children with Kawasaki disease. A logistic regression analysis was used to analyze the influencing factors of CAL in children with Kawasaki disease.ResultsIn total, 185 children with Kawasaki disease were included; the incidence of CAL in children with Kawasaki disease was 18.38%. Pearson’s correlation analysis showed that gender (r = 0.504), age (r = 0.611), duration of fever ≥10 days (r = 0.579), hemoglobin (Hb) (r = 0.623), and C-reactive protein (CRP) (r = 0.558) were all correlated with the CAL in children with Kawasaki disease (all p < 0.05). Logistic regression analyses showed that male [odds ratio (OR) = 2.543, 95% confidence interval (CI): 1.801–3.077, p = 0.040], age ≤2 years (OR = 3.002, 95% CI: 2.744–3.641, p = 0.012), duration of fever ≥10 days (OR = 2.089, 95% CI: 1.624–2.515, p = 0.028), Hb ≤105 g/L (OR = 1.914, 95% CI: 1.431–2.406, p = 0.013), and CRP ≥100 mg/L (OR = 2.168, 95% CI: 1.893–2.531, p = 0.035) were the risk factors of CAL in children with Kawasaki disease (all p < 0.05).ConclusionsThe incidence of CAL in children with Kawasaki disease is high and there are many related risk factors. Clinical medical workers should take early warning and carry out interventions and nursing care according to these risk factors to improve the prognosis of children with Kawasaki disease.https://www.frontiersin.org/articles/10.3389/fcvm.2024.1272475/fullcoronary artery lesionschildrenKawasaki diseasecaretreatment |
| spellingShingle | Cen Chen Qiuhui Chen Tong Zhang Yanping Ling Coronary artery lesions in children with Kawasaki disease: status quo and nursing care Frontiers in Cardiovascular Medicine coronary artery lesions children Kawasaki disease care treatment |
| title | Coronary artery lesions in children with Kawasaki disease: status quo and nursing care |
| title_full | Coronary artery lesions in children with Kawasaki disease: status quo and nursing care |
| title_fullStr | Coronary artery lesions in children with Kawasaki disease: status quo and nursing care |
| title_full_unstemmed | Coronary artery lesions in children with Kawasaki disease: status quo and nursing care |
| title_short | Coronary artery lesions in children with Kawasaki disease: status quo and nursing care |
| title_sort | coronary artery lesions in children with kawasaki disease status quo and nursing care |
| topic | coronary artery lesions children Kawasaki disease care treatment |
| url | https://www.frontiersin.org/articles/10.3389/fcvm.2024.1272475/full |
| work_keys_str_mv | AT cenchen coronaryarterylesionsinchildrenwithkawasakidiseasestatusquoandnursingcare AT qiuhuichen coronaryarterylesionsinchildrenwithkawasakidiseasestatusquoandnursingcare AT tongzhang coronaryarterylesionsinchildrenwithkawasakidiseasestatusquoandnursingcare AT yanpingling coronaryarterylesionsinchildrenwithkawasakidiseasestatusquoandnursingcare |