Enhanced Solubility and Biological Activity of Dexibuprofen-Loaded Silica-Based Ternary Solid Dispersions

Enhanced Solubility and Biological Activity of Dexibuprofen-Loaded Silica-Based Ternary Solid Dispersions

The current study was designed to formulate ternary solid dispersions (TSDs) of dexibuprofen (Dex) by solvent evaporation to augment the solubility and dissolution profile, in turn providing gastric protection and effective anti-inflammatory activity. Initially, nine formulations (S1 to S9) of binar...

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Bibliographic Details
Main Authors: Muhammad Asim, Marriam Nazir, Zunera Chauhdary, Muhammad Irfan, Syed Haroon Khalid, Sajid Asghar, Usra, Raed I. Felimban, Mohammed A Majrashi, Mohannad S. Hazzazi, Mohammed Alissa, Safa H Qahl, Ghulam Hussain, Azhar Rasul, Shahzad Ali Shahid Chatha, Ikram Ullah Khan
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Pharmaceutics
Subjects:
dexibuprofen
solid dispersions
Syloid 244FP<sup>®</sup>, Gelucire 48/16<sup>®</sup> and Poloxamer 188<sup>®</sup>
Online Access:https://www.mdpi.com/1999-4923/15/2/399

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https://www.mdpi.com/1999-4923/15/2/399

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