Intravenous injection of allogeneic umbilical cord-derived multipotent mesenchymal stromal cells reduces the infarct area and ameliorates cardiac function in a porcine model of acute myocardial infarction

Intravenous injection of allogeneic umbilical cord-derived multipotent mesenchymal stromal cells reduces the infarct area and ameliorates cardiac function in a porcine model of acute myocardial infarction

Abstract Background Multipotent mesenchymal stromal cell (MSC) therapy has been widely recognized as a feasible strategy for regenerating injured myocardial tissue. However, little is known about the efficacy of intravenous injection of allogeneic umbilical cord (UC) MSCs in preclinical models of po...

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Bibliographic Details
Main Authors: Meikuang Lim, Weiqiang Wang, Lu Liang, Zhi-bo Han, Zongjin Li, Jie Geng, Meng Zhao, Honghong Jia, Jie Feng, Zhe Wei, Baoquan Song, Jiemin Zhang, Jun Li, Tianwen Liu, Fan Wang, Ting Li, Jianming Li, Yihu Fang, Jianhua Gao, Zhongchao Han
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Stem Cell Research & Therapy
Subjects:
Umbilical cord
Multipotent mesenchymal stromal cell
Porcine
Acute myocardial infarction
Online Access:http://link.springer.com/article/10.1186/s13287-018-0888-z

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