Efficiency of photodynamic therapy in the treatment of peri-implantitis: A three-month randomized controlled clinical trial
Introduction. Peri-implantitis is an inflammatory lesion of peri-implant tissues. Eradication of the causative bacteria and decontamination of the implant surface is essential in achieving predictable and stabile clinical results. Photodynamic therapy (PDT) is non-invasive adjuvant therapeu...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Serbian Medical Society
2016-01-01
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| Series: | Srpski Arhiv za Celokupno Lekarstvo |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0370-8179/2016/0370-81791610478R.pdf |
| Summary: | Introduction. Peri-implantitis is an inflammatory lesion of peri-implant
tissues. Eradication of the causative bacteria and decontamination of the
implant surface is essential in achieving predictable and stabile clinical
results. Photodynamic therapy (PDT) is non-invasive adjuvant therapeutic
method to surgery in the treatment of bacterial infection. Objective. The aim
of this study was to evaluate early clinical and microbiological outcomes of
periimplantitis after surgical therapy with adjuvant PDT. Methods. Fifty-two
diagnosed peri-implantitis sites were divided into two groups. PDT was used
for decontamination of implant surface in the study group; in the control
group, chlorhexidine gel (CHX) followed by saline irrigation was applied.
Several clinical parameters were recorded before the treatment (baseline
values) and three months after surgical treatment. Samples for
microbiological identification were collected before therapy, during the
surgical therapy (before and after decontamination of implant surface), and
three months thereafter, and analyzed with identification systems using
biochemical analysis. Results. The use of PDT resulted in significant
decrease of bleeding on probing in comparison to CHX (p < 0.001). It showed
significant decontamination of implant surfaces with complete elimination of
anaerobic bacteria immediately after surgical procedure and three months
later. Conclusion. The results indicate that PDT can be used as an adjuvant
therapy to surgery for decontamination of implant surface and surrounding
peri-implant tissues within the treatment of peri-implantitis. [Projekat
Ministarstva nauke Republike Srbije, br. 41008] |
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| ISSN: | 0370-8179 2406-0895 |