Efficiency of photodynamic therapy in the treatment of peri-implantitis: A three-month randomized controlled clinical trial
Introduction. Peri-implantitis is an inflammatory lesion of peri-implant tissues. Eradication of the causative bacteria and decontamination of the implant surface is essential in achieving predictable and stabile clinical results. Photodynamic therapy (PDT) is non-invasive adjuvant therapeu...
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| Format: | Article |
| Language: | English |
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Serbian Medical Society
2016-01-01
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| Series: | Srpski Arhiv za Celokupno Lekarstvo |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0370-8179/2016/0370-81791610478R.pdf |
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| author | Rakašević Dragana Lazić Zoran Rakonjac Bojan Soldatović Ivan Janković Saša Magić Marko Aleksić Zoran |
| author_facet | Rakašević Dragana Lazić Zoran Rakonjac Bojan Soldatović Ivan Janković Saša Magić Marko Aleksić Zoran |
| author_sort | Rakašević Dragana |
| collection | DOAJ |
| description | Introduction. Peri-implantitis is an inflammatory lesion of peri-implant
tissues. Eradication of the causative bacteria and decontamination of the
implant surface is essential in achieving predictable and stabile clinical
results. Photodynamic therapy (PDT) is non-invasive adjuvant therapeutic
method to surgery in the treatment of bacterial infection. Objective. The aim
of this study was to evaluate early clinical and microbiological outcomes of
periimplantitis after surgical therapy with adjuvant PDT. Methods. Fifty-two
diagnosed peri-implantitis sites were divided into two groups. PDT was used
for decontamination of implant surface in the study group; in the control
group, chlorhexidine gel (CHX) followed by saline irrigation was applied.
Several clinical parameters were recorded before the treatment (baseline
values) and three months after surgical treatment. Samples for
microbiological identification were collected before therapy, during the
surgical therapy (before and after decontamination of implant surface), and
three months thereafter, and analyzed with identification systems using
biochemical analysis. Results. The use of PDT resulted in significant
decrease of bleeding on probing in comparison to CHX (p < 0.001). It showed
significant decontamination of implant surfaces with complete elimination of
anaerobic bacteria immediately after surgical procedure and three months
later. Conclusion. The results indicate that PDT can be used as an adjuvant
therapy to surgery for decontamination of implant surface and surrounding
peri-implant tissues within the treatment of peri-implantitis. [Projekat
Ministarstva nauke Republike Srbije, br. 41008] |
| first_indexed | 2024-12-17T21:10:53Z |
| format | Article |
| id | doaj.art-70b714a35ee6443a8bf3b75085255ed2 |
| institution | Directory Open Access Journal |
| issn | 0370-8179 2406-0895 |
| language | English |
| last_indexed | 2024-12-17T21:10:53Z |
| publishDate | 2016-01-01 |
| publisher | Serbian Medical Society |
| record_format | Article |
| series | Srpski Arhiv za Celokupno Lekarstvo |
| spelling | doaj.art-70b714a35ee6443a8bf3b75085255ed22022-12-21T21:32:27ZengSerbian Medical SocietySrpski Arhiv za Celokupno Lekarstvo0370-81792406-08952016-01-011449-1047848410.2298/SARH1610478R0370-81791610478REfficiency of photodynamic therapy in the treatment of peri-implantitis: A three-month randomized controlled clinical trialRakašević Dragana0Lazić Zoran1Rakonjac Bojan2Soldatović Ivan3Janković Saša4Magić Marko5Aleksić Zoran6Faculty of Dental Medicine, Department of Periodontology, BelgradeMedical Military Academy, Department of Oral Implantology, BelgradeMedical Military Academy, Institute of Microbiology, BelgradeSchool of Medicine, Institute of Medical Statistics and Informatics, BelgradeFaculty of Dental Medicine, Department of Periodontology, BelgradeFaculty of Dental Medicine, Department of Oral Surgery, BelgradeFaculty of Dental Medicine, Department of Periodontology, BelgradeIntroduction. Peri-implantitis is an inflammatory lesion of peri-implant tissues. Eradication of the causative bacteria and decontamination of the implant surface is essential in achieving predictable and stabile clinical results. Photodynamic therapy (PDT) is non-invasive adjuvant therapeutic method to surgery in the treatment of bacterial infection. Objective. The aim of this study was to evaluate early clinical and microbiological outcomes of periimplantitis after surgical therapy with adjuvant PDT. Methods. Fifty-two diagnosed peri-implantitis sites were divided into two groups. PDT was used for decontamination of implant surface in the study group; in the control group, chlorhexidine gel (CHX) followed by saline irrigation was applied. Several clinical parameters were recorded before the treatment (baseline values) and three months after surgical treatment. Samples for microbiological identification were collected before therapy, during the surgical therapy (before and after decontamination of implant surface), and three months thereafter, and analyzed with identification systems using biochemical analysis. Results. The use of PDT resulted in significant decrease of bleeding on probing in comparison to CHX (p < 0.001). It showed significant decontamination of implant surfaces with complete elimination of anaerobic bacteria immediately after surgical procedure and three months later. Conclusion. The results indicate that PDT can be used as an adjuvant therapy to surgery for decontamination of implant surface and surrounding peri-implant tissues within the treatment of peri-implantitis. [Projekat Ministarstva nauke Republike Srbije, br. 41008]http://www.doiserbia.nb.rs/img/doi/0370-8179/2016/0370-81791610478R.pdfperi-implantitisdecontaminationphotodynamic therapy |
| spellingShingle | Rakašević Dragana Lazić Zoran Rakonjac Bojan Soldatović Ivan Janković Saša Magić Marko Aleksić Zoran Efficiency of photodynamic therapy in the treatment of peri-implantitis: A three-month randomized controlled clinical trial Srpski Arhiv za Celokupno Lekarstvo peri-implantitis decontamination photodynamic therapy |
| title | Efficiency of photodynamic therapy in the treatment of peri-implantitis: A three-month randomized controlled clinical trial |
| title_full | Efficiency of photodynamic therapy in the treatment of peri-implantitis: A three-month randomized controlled clinical trial |
| title_fullStr | Efficiency of photodynamic therapy in the treatment of peri-implantitis: A three-month randomized controlled clinical trial |
| title_full_unstemmed | Efficiency of photodynamic therapy in the treatment of peri-implantitis: A three-month randomized controlled clinical trial |
| title_short | Efficiency of photodynamic therapy in the treatment of peri-implantitis: A three-month randomized controlled clinical trial |
| title_sort | efficiency of photodynamic therapy in the treatment of peri implantitis a three month randomized controlled clinical trial |
| topic | peri-implantitis decontamination photodynamic therapy |
| url | http://www.doiserbia.nb.rs/img/doi/0370-8179/2016/0370-81791610478R.pdf |
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